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Rong-Quan Xiao

Explore the profile of Rong-Quan Xiao including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 7
Citations 206
Followers 0
Related Specialties
Science
Biology
Cell Biology
Top 10 Co-Authors
Wen Liu
Wei-Wei Gao
Hai-Feng Shen
Bing-Ling Peng
Qi-Xuan Huang
Jian-Cheng Ding
Jia Yi
Wen-Juan Zhang
Ting Ran
Xiang Gao
Published In
Proc Natl Acad Sci U S A
J Theor Biol
Mol Cell
Theranostics
Sci Rep
Affiliations
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Recent Articles
1.
Peptide Inhibitor Targeting the Extraterminal Domain in BRD4 Potently Suppresses Breast Cancer Both and
Huang Q, Fan D, Zheng Z, Ran T, Bai A, Xiao R, et al.
J Med Chem . 2024 Apr; 67(8):6658-6672. PMID: 38569135
BRD4 is associated with a variety of human diseases, including breast cancer. The crucial roles of amino-terminal bromodomains (BDs) of BRD4 in binding with acetylated histones to regulate oncogene expression...
2.
A specific JMJD6 inhibitor potently suppresses multiple types of cancers both in vitro and in vivo
Xiao R, Ran T, Huang Q, Hu G, Fan D, Yi J, et al.
Proc Natl Acad Sci U S A . 2022 Aug; 119(34):e2200753119. PMID: 35969736
Jumonji C-domain-containing protein 6 (JMJD6), an iron (Fe) and α-ketoglutarate (α-KG)-dependent oxygenase, is expressed at high levels, correlated with poor prognosis, and considered as a therapeutic target in multiple cancer...
3.
A hypermethylation strategy utilized by enhancer-bound CARM1 to promote estrogen receptor α-dependent transcriptional activation and breast carcinogenesis
Peng B, Li W, Ding J, He Y, Ran T, Xie B, et al.
Theranostics . 2020 Mar; 10(8):3451-3473. PMID: 32206101
While protein arginine methyltransferases (PRMTs) and PRMT-catalyzed protein methylation have been well-known to be involved in a myriad of biological processes, their functions and the underlying molecular mechanisms in cancers,...
4.
JMJD6 Licenses ERα-Dependent Enhancer and Coding Gene Activation by Modulating the Recruitment of the CARM1/MED12 Co-activator Complex
Gao W, Xiao R, Zhang W, Hu Y, Peng B, Li W, et al.
Mol Cell . 2018 Apr; 70(2):340-357.e8. PMID: 29628309
Whereas the actions of enhancers in gene transcriptional regulation are well established, roles of JmjC-domain-containing proteins in mediating enhancer activation remain poorly understood. Here, we report that recruitment of the...
5.
Regulation of Transcription Factor Yin Yang 1 by SET7/9-mediated Lysine Methylation
Zhang W, Wu X, Shi T, Xu H, Yi J, Shen H, et al.
Sci Rep . 2016 Feb; 6:21718. PMID: 26902152
Yin Yang 1 (YY1) is a multifunctional transcription factor shown to be critical in a variety of biological processes. Although it is regulated by multiple types of post-translational modifications (PTMs),...
6.
Arginine methylation of HSP70 regulates retinoid acid-mediated RARβ2 gene activation
Gao W, Xiao R, Peng B, Xu H, Shen H, Huang M, et al.
Proc Natl Acad Sci U S A . 2015 Jun; 112(26):E3327-36. PMID: 26080448
Although "histone" methyltransferases and demethylases are well established to regulate transcriptional programs and to use nonhistone proteins as substrates, their possible roles in regulation of heat-shock proteins in the nucleus...
7.
Using the augmented Chou's pseudo amino acid composition for predicting protein submitochondria locations based on auto covariance approach
Zeng Y, Guo Y, Xiao R, Yang L, Yu L, Li M
J Theor Biol . 2009 Apr; 259(2):366-72. PMID: 19341746
The submitochondria location of a mitochondrial protein is very important for further understanding the structure and function of this protein. Hence, it is of great practical significance to develop an...