Ronald van Os
Overview
Explore the profile of Ronald van Os including associated specialties, affiliations and a list of published articles.
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35
Citations
1431
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Recent Articles
1.
Serrano Martinez P, Maimets M, Bron R, van Os R, de Haan G, Pringle S, et al.
iScience
. 2022 Sep;
25(10):105047.
PMID: 36147959
Stem/progenitor cells are required for maintenance of salivary gland (SG) function and serve as untapped reservoirs to create functional cells. Despite recent advancements in the identification of stem/progenitor pools, in...
2.
Rocchi C, Cinat D, Serrano Martinez P, Jellema-de Bruin A, Baanstra M, Brouwer U, et al.
Sci Signal
. 2021 Dec;
14(712):eabk0599.
PMID: 34874744
Salivary glands are damaged by radiotherapy for head and neck cancers, which often culminates in radiation-induced hyposalivation and xerostomia that may be permanent. Here, we identified a central role for...
3.
Cardoso A, Fernandes A, Aguilar-Pimentel J, de Angelis M, Guedes J, Brito M, et al.
Ageing Res Rev
. 2018 Aug;
47:214-277.
PMID: 30071357
Objective: Use of the frailty index to measure an accumulation of deficits has been proven a valuable method for identifying elderly people at risk for increased vulnerability, disease, injury, and...
4.
Lazare S, Ausema A, Reijne A, van Dijk G, van Os R, de Haan G
Exp Hematol
. 2017 Jun;
53:26-30.
PMID: 28625745
Hematopoietic stem cells (HSCs) undergo a profound functional decline during normal aging. Because caloric or dietary restriction has been shown to delay multiple aspects of the aging process in many...
5.
von Zglinicki T, Varela Nieto I, Brites D, Karagianni N, Ortolano S, Georgopoulos S, et al.
Mech Ageing Dev
. 2016 Jul;
160:34-40.
PMID: 27443148
Human life expectancy has increased dramatically in the last century and as a result also the prevalence of a variety of age-related diseases and syndromes. One such syndrome is frailty,...
6.
Pringle S, Maimets M, van der Zwaag M, Stokman M, van Gosliga D, Zwart E, et al.
Stem Cells
. 2016 Feb;
34(3):640-52.
PMID: 26887347
Adult stem cells are often touted as therapeutic agents in the regenerative medicine field, however data detailing both the engraftment and functional capabilities of solid tissue derived human adult epithelial...
7.
Maimets M, Rocchi C, Bron R, Pringle S, Kuipers J, Giepmans B, et al.
Stem Cell Reports
. 2016 Jan;
6(1):150-62.
PMID: 26724906
Adult stem cells are the ultimate source for replenishment of salivary gland (SG) tissue. Self-renewal ability of stem cells is dependent on extrinsic niche signals that have not been unraveled...
8.
Maimets M, Bron R, de Haan G, van Os R, Coppes R
Radiother Oncol
. 2015 Jul;
116(3):443-8.
PMID: 26138058
Background And Purpose: Salivary gland dysfunction is a major side effect of radiotherapy for head and neck cancer patients, which in the future might be salvaged by autologous adult salivary...
9.
Nanduri L, Baanstra M, Faber H, Rocchi C, Zwart E, de Haan G, et al.
Stem Cell Reports
. 2014 Dec;
3(6):957-64.
PMID: 25448065
Hyposalivation often leads to irreversible and untreatable xerostomia. Salivary gland (SG) stem cell therapy is an attractive putative option to salvage these patients but is impeded by the limited availability...
10.
de Kruijf E, Alkemade G, van Os R, Fibbe W, van Pel M
Int J Hematol
. 2014 Apr;
99(6):714-20.
PMID: 24752699
Granulocyte-colony-stimulating factor (G-CSF)-induced hematopoietic stem and progenitor cell (HSPC) mobilization is associated with the release of neutrophil-derived proteases. Previously, we have shown that alpha-1-antitrypsin (AAT) inhibits these proteases in mice,...