Ronald E Cannon
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Explore the profile of Ronald E Cannon including associated specialties, affiliations and a list of published articles.
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29
Citations
605
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Recent Articles
1.
Banks D, Lierz S, Cannon R, Korach K
Endocrinology
. 2024 Jul;
165(8).
PMID: 38984714
The blood-brain barrier (BBB) is an extensive capillary network that protects the brain from environmental and metabolic toxins while limiting drug delivery to the central nervous system (CNS). The ATP-binding...
2.
Brown S, Sinha B, Cannon R
Cancers (Basel)
. 2024 May;
16(9).
PMID: 38730685
The blood-brain barrier is composed of both a physical barrier and an enzymatic barrier. Tight junction (TJ) proteins expressed between endothelial cells of brain capillaries provide the physical barrier to...
3.
Sinha B, Bortner C, Jarmusch A, Tokar E, Murphy C, Wu X, et al.
Cells
. 2023 Jun;
12(12).
PMID: 37371096
Our recent studies show that the treatment of human ovarian tumor cells with NCX4040 results in significant depletions of cellular glutathione, the formation of reactive oxygen/nitrogen species and cell death....
4.
Sinha B, Perera L, Cannon R
Cancers (Basel)
. 2021 Apr;
13(7).
PMID: 33918289
The emergence of multidrug resistance (MDR) in the clinic is a significant problem for a successful treatment of human cancers. Overexpression of various ABC transporters (P-gp, BCRP and MRP's), which...
5.
Cannon R, Richards A, Trexler A, Juberg C, Sinha B, Knudsen G, et al.
Environ Health Perspect
. 2020 Mar;
128(3):37002.
PMID: 32212926
Background: Ammonium 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid (GenX) is a replacement for perfluorooctanoic acid in the production of fluoropolymers used in a variety of consumer products. GenX alters fetal development and antibody production...
6.
Sinha B, Perera L, Cannon R
Biomed Pharmacother
. 2019 Oct;
120:109468.
PMID: 31605952
Development of resistance to chemotherapy drugs is a significant problem in treating human malignancies in the clinic. Overexpression of ABC transporter proteins, including P-170 glycoprotein (P-gp), and breast cancer resistance...
7.
Trexler A, Knudsen G, Nicklisch S, Birnbaum L, Cannon R
Toxicol Sci
. 2019 Aug;
171(2):463-472.
PMID: 31368499
2,4,6-Tribromophenol (TBP, CAS No. 118-79-6) is a brominated chemical used in the production of flame-retardant epoxy resins and as a wood preservative. In marine environments, TBP is incorporated into shellfish...
8.
Cannon R, Trexler A, Knudsen G, Evans R, Birnbaum L
Toxicol Sci
. 2019 Mar;
169(2):475-484.
PMID: 30830211
Tetrabromobisphenol A (TBBPA, CAS No. 79-94-7) is a brominated flame retardant used in 90% of epoxy coated circuit boards. Exposures to TBBPA can induce neurotoxicity and disrupt MAPK, estrogen, thyroid,...
9.
Sinha B, Bortner C, Mason R, Cannon R
Biochim Biophys Acta Gen Subj
. 2018 Sep;
1862(12):2806-2814.
PMID: 30251669
Background: Development of resistance to chemotherapy drugs is a significant problem in treating human malignancies in the clinic. Overexpression of drug efflux proteins, including P-170 glycoprotein (P-gp), an ATP-dependent efflux...
10.
Banks D, Chan G, Evans R, Miller D, Cannon R
J Cereb Blood Flow Metab
. 2017 Apr;
38(5):857-868.
PMID: 28447863
The blood-brain barrier is a microvascular network that (1) provides neuroprotection from metabolic and environmental toxins and (2) limits the delivery of therapeutics to the central nervous system (CNS). The...