Romina Fiorotto
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Explore the profile of Romina Fiorotto including associated specialties, affiliations and a list of published articles.
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50
Citations
1642
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Recent Articles
1.
Prominent role of gut dysbiosis in the pathogenesis of cystic fibrosis-related liver disease in mice
Bertolini A, Nguyen M, Zehra S, Taleb S, Bauer-Pisani T, Palm N, et al.
J Hepatol
. 2024 Mar;
81(3):429-440.
PMID: 38554847
Background & Aims: Cystic fibrosis-related liver disease (CFLD) is a chronic cholangiopathy that increases morbidity and mortality in patients with CF. Current treatments are unsatisfactory, and incomplete understanding of CFLD...
2.
Fiorotto R, Mariotti V, Taleb S, Zehra S, Nguyen M, Amenduni M, et al.
Hepatol Commun
. 2023 Mar;
7(4).
PMID: 36972396
Background And Aims: Cholangiopathies are an important cause of morbidity and mortality. Their pathogenesis and treatment remain unclear in part because of the lack of disease models relevant to humans....
3.
Gouon-Evans V, Fiorotto R
Hepatology
. 2022 Aug;
77(5):1469-1471.
PMID: 35957526
No abstract available.
4.
Rodrigues M, Gomes D, Fiorotto R, Guerra M, Weerachayaphorn J, Bo T, et al.
Hepatol Commun
. 2022 Jul;
6(10):2748-2764.
PMID: 35852334
Fluid and bicarbonate secretion is a principal function of cholangiocytes, and impaired secretion results in cholestasis. Cholangiocyte secretion depends on peri-apical expression of the type 3 inositol trisphosphate receptor (ITPR3),...
5.
Fabris L, Milani C, Fiorotto R, Mariotti V, Kaffe E, Seller B, et al.
FASEB J
. 2022 May;
36(6):e22364.
PMID: 35593740
Congenital hepatic fibrosis (CHF), a genetic cholangiopathy characterized by fibropolycystic changes in the biliary tree, is caused by mutations in the PKHD1 gene, leading to defective fibrocystin (FPC), changes in...
6.
Bertolini A, Fiorotto R, Strazzabosco M
Semin Immunopathol
. 2022 Apr;
44(4):547-564.
PMID: 35415765
Bile acids participate in the intestinal emulsion, digestion, and absorption of lipids and fat-soluble vitamins. When present in high concentrations, as in cholestatic liver diseases, bile acids can damage cells...
7.
Mariotti V, Fiorotto R, Cadamuro M, Fabris L, Strazzabosco M
JHEP Rep
. 2021 Jun;
3(3):100251.
PMID: 34151244
The family of vascular endothelial growth factors (VEGFs) includes 5 members (VEGF-A to -D, and placenta growth factor), which regulate several critical biological processes. VEGF-A exerts a variety of biological...
8.
Oliveira A, Fiorotto R
Transl Gastroenterol Hepatol
. 2021 Apr;
6:19.
PMID: 33824923
Lack of a prompt and accurate diagnosis remains on top of the list of challenges faced by patients with rare liver diseases. Although rare liver diseases affect a significant percentage...
9.
Stein S, Henze L, Poch T, Carambia A, Krech T, Preti M, et al.
J Hepatol
. 2020 Nov;
74(4):919-930.
PMID: 33197512
Background & Aims: IL-17A-producing T cells are present in autoimmune cholestatic liver diseases; however, little is known about the contribution of IL-17 to periductal immune responses. Herein, we investigated the...
10.
Bertolini A, Van de Peppel I, Bodewes F, Moshage H, Fantin A, Farinati F, et al.
Hepatology
. 2020 Jul;
72(5):1864-1872.
PMID: 32702162
No abstract available.