Roger van Groenendael
Overview
Explore the profile of Roger van Groenendael including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
12
Citations
107
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Beunders R, Donato L, van Groenendael R, Arlt B, Carvalho-Wodarz C, Schulte J, et al.
Kidney Int Rep
. 2023 Nov;
8(11):2345-2355.
PMID: 38025210
Introduction: In clinical practice, kidney (dys)function is monitored through creatinine-based estimations of glomerular filtration rate (eGFR: Modification of Diet in Renal Disease [MDRD], Chronic Kidney Disease Epidemiology Collaboration [CKD-EPI]). Creatinine...
2.
Habes Q, Kant N, Beunders R, van Groenendael R, Gerretsen J, Kox M, et al.
Heart Lung Circ
. 2023 Jan;
32(3):395-404.
PMID: 36621395
Background: Approximately half of patients who undergo cardiac surgery develop systemic inflammatory response syndrome. Extracorporeal circulation and intestinal injury may play a role in this inflammatory response, although their relative...
3.
van Groenendael R, Beunders R, Hemelaar P, Hofland J, Morshuis W, van der Hoeven J, et al.
Crit Care Med
. 2021 Feb;
49(5):790-803.
PMID: 33591006
Objectives: To determine the safety and efficacy of human chorionic gonadotropin hormone-derivative EA-230 in cardiac surgery patients. Cardiac surgery induces systemic inflammation and may impair renal function, affecting patient outcome....
4.
Beunders R, Schutz M, van Groenendael R, Leijte G, Kox M, van Eijk L, et al.
Front Med (Lausanne)
. 2020 Nov;
7:559671.
PMID: 33251227
Sepsis is the most prevalent cause of Acute Kidney Injury (AKI). Conversely, in some septic patients the glomerular filtration rate (GFR) is augmented. The role of the inflammatory response and...
5.
Beunders R, van Groenendael R, Leijte G, Kox M, Pickkers P
Shock
. 2020 Jan;
54(3):308-314.
PMID: 31977957
Background: The assessment of renal function in clinical practice remains challenging. Using creatinine to assess the glomerular filtration rate (GFR) is notoriously inaccurate, and determination of the true GFR, e.g.,...
6.
van Groenendael R, Beunders R, Kox M, van Eijk L, Pickkers P
Semin Nephrol
. 2019 Sep;
39(5):496-504.
PMID: 31514913
The extent of the systemic inflammatory response following infectious or noninfectious insults is related to impaired patient outcome. Pregnancy is associated with immunotolerance and an increased glomerular filtration rate. EA-230...
7.
van Groenendael R, Aarnoutse R, Kox M, Van Eijk L, Pickkers P
Br J Clin Pharmacol
. 2019 Mar;
85(7):1572-1584.
PMID: 30924163
Aims: EA-230 is a newly developed synthetic linear tetrapeptide (AQGV) derived from the chorionic gonadotropin hormone (β-hCG). We investigated the pharmacokinetics, safety and tolerability of EA-230 in healthy subjects using...
8.
van Groenendael R, Kox M, Leijte G, Koeneman B, Gerretsen J, Van Eijk L, et al.
Br J Clin Pharmacol
. 2019 Mar;
85(7):1559-1571.
PMID: 30919998
Aims: EA-230 is a human chorionic gonadotropin hormone-derived linear tetrapeptide, developed for the treatment of systemic inflammation-related disorders. EA-230 has shown promising immunomodulatory and tissue-protective effects in animals and an...
9.
van Groenendael R, Beunders R, Hofland J, Morshuis W, Kox M, van Eijk L, et al.
JMIR Res Protoc
. 2019 Feb;
8(2):e11441.
PMID: 30724734
Background: The cardiac surgery-induced systemic inflammatory response may induce postoperative hemodynamic instability and impairment of renal function. EA-230, a linear tetrapeptide (A-Q-G-V), is derived from the beta chain of the...
10.
van Groenendael R, Kox M, van Eijk L, Pickkers P
Nephron
. 2018 Jul;
140(2):148-151.
PMID: 29982253
The systemic inflammatory response following infectious or non-infectious insults is related to morbidity (including acute kidney injury) and mortality. Pregnancy is associated with immunotolerance and an increased glomerular filtration rate....