Roger M Burnett
Overview
Explore the profile of Roger M Burnett including associated specialties, affiliations and a list of published articles.
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17
Citations
708
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Recent Articles
1.
Rux J, Burnett R
Methods Mol Med
. 2007 Jul;
131:231-50.
PMID: 17656787
This chapter provides a protocol for the large-scale purification of adenovirus type 2 and 5 virions and the soluble major coat protein hexon. The purified virus particles remain intact and...
2.
Pichla-Gollon S, Drinker M, Zhou X, Xue F, Rux J, Gao G, et al.
J Virol
. 2006 Nov;
81(4):1680-9.
PMID: 17108028
Virus-specific neutralizing antibodies present an obstacle to the effective use of adenovirus vectors for gene therapy and vaccination. The specific sites recognized by neutralizing antibodies have not been identified for...
3.
Xu L, Benson S, Burnett R
J Struct Biol
. 2006 Oct;
157(2):424-31.
PMID: 17071105
CELO (chicken embryo lethal orphan) virus is an avian adenovirus that is being developed as a gene transfer vector. Its trimeric major coat protein (942 residues, 106,709 Da) has 42%...
4.
Xue F, Burnett R
J Struct Biol
. 2006 Feb;
154(2):217-21.
PMID: 16458021
The major coat protein, hexon, from a chimpanzee adenovirus (AdC68) is of interest as a target for vaccine vector modification. AdC68 hexon has been crystallized in the orthorhombic space group...
5.
6.
Saren A, Ravantti J, Benson S, Burnett R, Paulin L, Bamford D, et al.
J Mol Biol
. 2005 Jun;
350(3):427-40.
PMID: 15946683
The origin, evolution and relationships of viruses are all fascinating topics. Current thinking in these areas is strongly influenced by the tailed double-stranded (ds) DNA bacteriophages. These viruses have mosaic...
7.
Scheres S, Marabini R, Lanzavecchia S, Cantele F, Rutten T, Fuller S, et al.
J Struct Biol
. 2005 Jun;
151(1):79-91.
PMID: 15923127
We present a novel strategy for classification of heterogeneous electron microscopy data of icosahedral virus particles. The effectiveness of the procedure, which is based on classification of single-projection reconstructions (SPRs),...
8.
Rux J, Burnett R
Hum Gene Ther
. 2005 Feb;
15(12):1167-76.
PMID: 15684694
Structural studies continue to play an essential role as the focus of adenovirus research shifts in emphasis from basic biology to adenovirus-based vector technologies. A crucial step in developing novel...
9.
Benson S, Bamford J, Bamford D, Burnett R
Mol Cell
. 2004 Dec;
16(5):673-85.
PMID: 15574324
Our discovery that the major coat protein of bacteriophage PRD1 resembles that of human adenovirus raised the unexpected possibility that viruses infecting bacteria could be related by evolution to those...
10.
Abrescia N, Cockburn J, Grimes J, Sutton G, Diprose J, Butcher S, et al.
Nature
. 2004 Nov;
432(7013):68-74.
PMID: 15525981
The structure of the membrane-containing bacteriophage PRD1 has been determined by X-ray crystallography at about 4 A resolution. Here we describe the structure and location of proteins P3, P16, P30...