Roger L Clem
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Explore the profile of Roger L Clem including associated specialties, affiliations and a list of published articles.
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37
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1532
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Recent Articles
1.
Lacagnina A, Dong T, Iyer R, Boesch L, Khan S, Mohamed M, et al.
Cell Rep
. 2024 Oct;
43(11):114880.
PMID: 39425930
Contextual memories are critical for survival but must be extinguished when new conditions render them nonproductive. By most accounts, extinction forms a new memory that competes with the original association...
2.
Zeisler Z, Heslin K, Stoll F, Hof P, Clem R, Rudebeck P
Curr Biol
. 2024 Jul;
34(14):3249-3257.e3.
PMID: 38964318
Basolateral amygdala (BLA) is a key hub for affect in the brain, and dysfunction within this area contributes to a host of psychiatric disorders. BLA is extensively and reciprocally interconnected...
3.
Campos-Cardoso R, Desa Z, Fitzgerald B, Moore A, Duhon J, Landar V, et al.
Cell Rep
. 2024 Apr;
43(4):114097.
PMID: 38613783
The rodent medial prefrontal cortex (mPFC) is functionally organized across the dorsoventral axis, where dorsal and ventral subregions promote and suppress fear, respectively. As the ventral-most subregion, the dorsal peduncular...
4.
Zeisler Z, Heslin K, Stoll F, Hof P, Clem R, Rudebeck P
bioRxiv
. 2024 Jan;
PMID: 38187599
The basolateral amygdala (BLA) projects to the frontal cortex (FC) in both rodents and primates, but the comparative organization of single-neuron BLA-FC projections is unknown. Using a barcoded connectomic approach,...
5.
Lacagnina A, Dong T, Iyer R, Khan S, Mohamed M, Clem R
bioRxiv
. 2023 Dec;
PMID: 38077077
Contextual associations are critical for survival but must be extinguished when new conditions render them nonproductive. By most accounts, extinction forms a new memory that competes with the original association...
6.
Zeisler Z, London L, Janssen W, Fredericks J, Elorette C, Fujimoto A, et al.
Neuron
. 2023 Oct;
111(20):3307-3320.e5.
PMID: 37857091
Basolateral amygdala (BLA) projects widely across the macaque frontal cortex, and amygdalo-frontal projections are critical for appropriate emotional responding and decision making. While it is appreciated that single BLA neurons...
7.
Cardoso R, Desa Z, Fitzgerald B, Moore A, Duhon J, Landar V, et al.
bioRxiv
. 2023 Aug;
PMID: 37546717
The rodent medial prefrontal cortex (mPFC) is a locus for both the promotion and suppression (e.g. extinction) of fear and is composed of four anatomically distinct subregions, including anterior cingulate...
8.
Zeisler Z, London L, Janssen W, Fredericks J, Elorette C, Fujimoto A, et al.
bioRxiv
. 2023 Jan;
PMID: 36711708
The basolateral amygdala (BLA) projects widely across the macaque frontal cortex, and amygdalo-frontal projections are critical for optimal emotional responding and decision-making. Yet, little is known about the single-neuron architecture...
9.
Chen L, Francisco T, Baggetta A, Zaki Y, Ramirez S, Clem R, et al.
Neurobiol Aging
. 2023 Jan;
123:92-97.
PMID: 36652783
With the prevalence of age-related cognitive deficits on the rise, it is essential to identify cellular and circuit alterations that contribute to age-related memory impairment. Increased intrinsic neuronal excitability after...
10.
Cummings K, Bayshtok S, Dong T, Kenny P, Clem R
Neuron
. 2022 Aug;
110(18):3036-3052.e5.
PMID: 35944526
Neurons activated by learning have been ascribed the unique potential to encode memory, but the functional contribution of discrete cell types remains poorly understood. In particular, it is unclear whether...