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Rodrigo Villares Portugal

Explore the profile of Rodrigo Villares Portugal including associated specialties, affiliations and a list of published articles. Areas
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Articles 18
Citations 175
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Recent Articles
1.
Adamoski D, Dias M, Quesnay J, Yang Z, Zagoriy I, Steyer A, et al.
Nat Struct Mol Biol . 2023 Oct; 30(12):1902-1912. PMID: 37857822
Glutaminase (GLS), which deaminates glutamine to form glutamate, is a mitochondrial tetrameric protein complex. Although inorganic phosphate (Pi) is known to promote GLS filamentation and activation, the molecular basis of...
2.
Nunes S, Silva J, Fernandes R, Miranda S, Leite E, de Farias M, et al.
Pharmaceutics . 2022 Feb; 14(2). PMID: 35214005
PEGylated liposomes are largely studied as long-circulating drug delivery systems. Nevertheless, the addition of PEG can result in reduced interactions between liposomes and cells, hindering liposomal internalization into target cells....
3.
Ribeiro-Filho H, Coimbra L, Cassago A, Rocha R, Guerra J, de Felicio R, et al.
Nat Commun . 2021 May; 12(1):3038. PMID: 34031424
Mayaro virus (MAYV) is an emerging arbovirus of the Americas that may cause a debilitating arthritogenic disease. The biology of MAYV is not fully understood and largely inferred from related...
4.
Higa L, Schilrreff P, Briski A, Jerez H, de Farias M, Portugal R, et al.
Colloids Surf B Biointerfaces . 2020 Mar; 191:110961. PMID: 32208325
Oral administration of antioxidant and anti-inflammatory drugs have the potential to improve the current therapy of inflammatory bowel disease. Success of oral treatments, however, depends on the capacity of drugs...
5.
Souza Junior J, Schleder G, Colombari F, de Farias M, Bettini J, van Heel M, et al.
J Phys Chem Lett . 2020 Feb; 11(4):1564-1569. PMID: 32023063
In recent years, cryogenic electron microscopy (Cryo-EM) has revolutionized the structure determination of wet samples and especially that of biological macromolecules. The glassy-water medium in which the molecules are embedded...
6.
Schilrreff P, Simioni Y, Jerez H, Caimi A, de Farias M, Portugal R, et al.
Colloids Surf B Biointerfaces . 2019 Apr; 179:479-487. PMID: 31005743
Oxidative stress plays an essential role in the pathogenesis and progression of inflammatory bowel disease. Co-administration of antioxidants and anti-inflammatory drugs has shown clinical benefits. Due to its significant reactive...
7.
Perez A, Perez N, Lozano C, Altube M, de Farias M, Portugal R, et al.
Phytomedicine . 2019 Mar; 57:339-351. PMID: 30826631
Background: Thymus vulgaris essential oil (T) could be an alternative to classical antibiotics against bacterial biofilms, which show increased tolerance to antibiotics and host defence systems and contribute to the...
8.
Caimi A, Altube M, de Farias M, Portugal R, Perez A, Romero E, et al.
Colloids Surf B Biointerfaces . 2018 Dec; 174:536-543. PMID: 30500742
Development of needle and pain free noninvasive immunization procedures is a top priority for public health agencies. In this work the topical adjuvant activity of the immunomodulator imiquimod (IMQ) carried...
9.
Parra F, Caimi A, Altube M, Cargnelutti D, Vermeulen M, de Farias M, et al.
Front Bioeng Biotechnol . 2018 Nov; 6:163. PMID: 30460231
Hyperhalophilic archaebacteria exclusively produce sn2,3 diphytanylglycerol diether archaeolipids, unique structures absent in bacteria and eukaryotes. Nanovesicles made of archaeolipids known as nanoarchaeosomes (nanoARC), possess highly stable bilayers, some of them...
10.
Karpel R, da Silva Liberato M, Campeiro J, Bergeon L, Szychowski B, Butler A, et al.
Colloids Surf B Biointerfaces . 2017 Dec; 163:1-8. PMID: 29268209
This paper describes the development of a facile and environmentally friendly strategy for supporting crotamine on gold nanoparticles (GNPs). Our approach was based on the covalent binding interaction between the...