Rodolphe R Guinamard
Overview
Explore the profile of Rodolphe R Guinamard including associated specialties, affiliations and a list of published articles.
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13
Citations
260
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Recent Articles
1.
Gallerand A, Stunault M, Merlin J, Guinamard R, Yvan-Charvet L, Ivanov S
Immunometabolism
. 2024 Dec;
2(4):immunometab20200028.
PMID: 39649554
Myeloid cells are key contributors to tissue, immune and metabolic homeostasis and their alteration fuels inflammation and associated disorders such as atherosclerosis. Conversely, in a classical chicken-and-egg situation, systemic and...
2.
Gallerand A, Dolfi B, Stunault M, Caillot Z, Castiglione A, Strazzulla A, et al.
Nat Commun
. 2024 Oct;
15(1):9027.
PMID: 39424804
Monocytes directly contribute to atherosclerosis development by their recruitment to plaques in which they differentiate into macrophages. In the present study, we ask how modulating monocyte glucose metabolism could affect...
3.
Dolfi B, Gallerand A, Caillot Z, Castiglione A, Zair F, Leporati L, et al.
Eur J Immunol
. 2024 May;
54(8):e2350851.
PMID: 38803021
Stress exposure has been shown to modulate innate and adaptive immune responses. Indeed, stress favors myelopoiesis and monocyte generation and contributes to cardiovascular disease development. As sex hormones regulate innate...
4.
Dolfi B, Gallerand A, Firulyova M, Xu Y, Merlin J, Dumont A, et al.
Cell Rep
. 2022 Jun;
39(11):110949.
PMID: 35705045
Despite the ubiquitous function of macrophages across the body, the diversity, origin, and function of adrenal gland macrophages remain largely unknown. We define the heterogeneity of adrenal gland immune cells...
5.
Merlin J, Ivanov S, Dumont A, Sergushichev A, Gall J, Stunault M, et al.
Nat Metab
. 2021 Oct;
3(10):1313-1326.
PMID: 34650273
Macrophages rely on tightly integrated metabolic rewiring to clear dying neighboring cells by efferocytosis during homeostasis and disease. Here we reveal that glutaminase-1-mediated glutaminolysis is critical to promote apoptotic cell...
6.
Gallerand A, Stunault M, Merlin J, Luehmann H, Sultan D, Firulyova M, et al.
Nat Commun
. 2021 Sep;
12(1):5255.
PMID: 34489438
Monocytes are part of the mononuclear phagocytic system. Monocytes play a central role during inflammatory conditions and a better understanding of their dynamics might open therapeutic opportunities. In the present...
7.
Dolfi B, Gallerand A, Haschemi A, Guinamard R, Ivanov S
Atherosclerosis
. 2021 Aug;
334:1-8.
PMID: 34450556
Metabolism plays a key role in controlling immune cell functions. In this review, we will discuss the diversity of plaque resident myeloid cells and will focus on their metabolic demands...
8.
Dufies O, Doye A, Courjon J, Torre C, Michel G, Loubatier C, et al.
Nat Microbiol
. 2021 Jan;
6(3):401-412.
PMID: 33432150
Inflammasomes are signalling platforms that are assembled in response to infection or sterile inflammation by cytosolic pattern recognition receptors. The consequent inflammasome-triggered caspase-1 activation is critical for the host defence...
9.
Ivanov S, Gallerand A, Gros M, Stunault M, Merlin J, Vaillant N, et al.
Eur J Immunol
. 2019 Jun;
49(11):2012-2018.
PMID: 31251389
Macrophages play a central role during infection, inflammation and tissue homeostasis maintenance. Macrophages have been identified in all organs and their core transcriptomic signature and functions differ from one tissue...
10.
Stunault M, Bories G, Guinamard R, Ivanov S
Mediators Inflamm
. 2019 Jan;
2018:2426138.
PMID: 30647530
Monocyte and macrophage diversity is evidenced by the modulation of cell surface markers and differential production of soluble mediators. These immune cells play key roles in controlling tissue homeostasis, infections,...