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Rodney P OConnor

Explore the profile of Rodney P OConnor including associated specialties, affiliations and a list of published articles. Areas
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Articles 19
Citations 183
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Recent Articles
1.
Blazic A, Guinard M, Leskovar T, OConnor R, Rems L
Bioelectrochemistry . 2024 Sep; 161:108802. PMID: 39243733
Electroporation causes a temporal increase in cell membrane permeability and leads to prolonged changes in transmembrane voltage (TMV) in both excitable and non-excitable cells. However, the mechanisms of these TMV...
2.
Batista Napotnik T, Kos B, Jarm T, Miklavcic D, OConnor R, Rems L
Sci Rep . 2024 Jan; 14(1):720. PMID: 38184741
Electric pulses used in electroporation-based treatments have been shown to affect the excitability of muscle and neuronal cells. However, understanding the interplay between electroporation and electrophysiological response of excitable cells...
3.
Lefevre M, Kaszas A, Dijk G, Baca M, Baudino O, Marchiori B, et al.
J Vis Exp . 2022 Aug; (186). PMID: 36036582
Glioblastoma is difficult to eradicate with standard oncology therapies due to its high degree of invasiveness. Bioelectric treatments based on pulsed electric fields (PEFs) are promising for the improvement of...
4.
Poulkouras R, Dijk G, Lefevre M, Baca M, Moreau D, OConnor R
Bioelectrochemistry . 2022 Jun; 147:108163. PMID: 35665621
Glioblastoma Multiforme is a highly lethal form of brain cancer, resistant to traditional therapeutic approaches and oftentimes hardly resectable. The application of pulsed electric fields (PEF) is gaining prominence as...
5.
Dijk G, Poulkouras R, OConnor R
IEEE Trans Biomed Eng . 2022 Jan; 69(7):2363-2369. PMID: 35041593
Objective: Monitoring of impedance changes during electroporation-based treatments can be used to study the biological response and provide feedback regarding treatment progression. However, seamless integration of the sensing electrodes with...
6.
Navickaite D, Ruzgys P, Maciulevicius M, Dijk G, OConnor R, Satkauskas S
Bioelectrochemistry . 2021 Aug; 142:107927. PMID: 34425390
The combination of Ca ions and electroporation has gained attention as potential alternative to electrochemotherapy. Ca is an important component of the cell membrane repair system and its presence directly...
7.
Pas J, Rutz A, Quilichini P, Slezia A, Ghestem A, Kaszas A, et al.
J Neural Eng . 2018 Aug; 15(6):065001. PMID: 30132444
Objective: Neural electrophysiology is often conducted with traditional, rigid depth probes. The mechanical mismatch between these probes and soft brain tissue is unfavorable for tissue interfacing. Making probes compliant can...
8.
Carr L, Bardet S, Arnaud-Cormos D, Leveque P, OConnor R
Bioelectrochemistry . 2017 Sep; 119:68-75. PMID: 28917183
Cytosolic, synthetic chemical calcium indicators are typically used to visualise the rapid increase in intracellular calcium ion concentration that follows nanosecond pulsed electric field (nsPEF) application. This study looks at...
9.
Moreau D, Lefort C, Pas J, Bardet S, Leveque P, OConnor R
J Biophotonics . 2017 Jul; 11(2). PMID: 28700117
The influence of infrared laser pulses on intracellular Ca signaling was investigated in neural cell lines with fluorescent live cell imaging. The probe Fluo-4 was used to measure Ca in...
10.
Burke R, Bardet S, Carr L, Romanenko S, Arnaud-Cormos D, Leveque P, et al.
Biochim Biophys Acta Biomembr . 2017 Jul; 1859(10):2040-2050. PMID: 28693898
Nanosecond pulsed electric fields (nsPEFs) have a variety of applications in the biomedical and biotechnology industries. Cancer treatment has been at the forefront of investigations thus far as nsPEFs permeabilize...