Robin Lescure
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Explore the profile of Robin Lescure including associated specialties, affiliations and a list of published articles.
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16
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Recent Articles
1.
A Versatile "Synthesis Tag" (SynTag) for the Chemical Synthesis of Aggregating Peptides and Proteins
Burgisser H, Williams E, Jeandin A, Lescure R, Premanand A, Wang S, et al.
J Am Chem Soc
. 2024 Dec;
146(50):34887-34899.
PMID: 39639492
Solid-phase peptide synthesis (SPPS) and native chemical ligation (NCL) are powerful methods for obtaining peptides and proteins that are otherwise inaccessible. Nonetheless, numerous sequences are difficult to prepare via SPPS,...
2.
Privat M, Bellaye P, Lescure R, Massot A, Baffroy O, Moreau M, et al.
J Med Chem
. 2021 Aug;
64(15):11063-11073.
PMID: 34338511
A water-soluble fluorescent aza-BODIPY platform (Wazaby) was prepared and functionalized by a polyazamacrocycle agent and a bioconjugable arm. The resulting fluorescent derivative was characterized and bioconjugated onto a trastuzumab monoclonal...
3.
Lescure R, Privat M, Pliquett J, Massot A, Baffroy O, Busser B, et al.
Eur J Med Chem
. 2021 Apr;
220:113483.
PMID: 33915372
Three near-infrared (NIR-I) optical theranostic systems were synthesized, characterized and studied in vitro and in vivo. These original homo-bimetallic gold(I)-based aza-BODIPY complexes proved to be trackable through near-infrared optical imaging...
4.
Flores O, Pliquett J, Abad Galan L, Lescure R, Denat F, Maury O, et al.
Inorg Chem
. 2020 Jan;
59(2):1306-1314.
PMID: 31909995
In this study, an original aza-BODIPY system comprising two Gd complexes has been designed and synthesized for magnetic resonance imaging/optical imaging applications, by functionalization of the boron center. This strategy...
5.
Pliquett J, Dubois A, Racoeur C, Mabrouk N, Amor S, Lescure R, et al.
Bioconjug Chem
. 2019 Jan;
30(4):1061-1066.
PMID: 30615430
A new family of water-soluble and bioconjugatable aza-BODIPY fluorophores was designed and synthesized using a boron- functionalization strategy. These dissymmetric bis-ammonium aza-BODIPY dyes present optimal properties for a fluorescent probe;...