Robin D S Doddrell
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Explore the profile of Robin D S Doddrell including associated specialties, affiliations and a list of published articles.
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5
Citations
403
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Recent Articles
1.
Sox2 expression in Schwann cells inhibits myelination and induces influx of macrophages to the nerve
Roberts S, Dun X, Doddrell R, Mindos T, Drake L, Onaitis M, et al.
Development
. 2017 Jul;
144(17):3114-3125.
PMID: 28743796
Correct myelination is crucial for the function of the peripheral nervous system. Both positive and negative regulators within the axon and Schwann cell function to ensure the correct onset and...
2.
Mindos T, Dun X, North K, Doddrell R, Schulz A, Edwards P, et al.
J Cell Biol
. 2017 Feb;
216(2):495-510.
PMID: 28137778
Loss of the Merlin tumor suppressor and activation of the Hippo signaling pathway play major roles in the control of cell proliferation and tumorigenesis. We have identified completely novel roles...
3.
Doddrell R, Dun X, Shivane A, Feltri M, Wrabetz L, Wegner M, et al.
Brain
. 2013 Feb;
136(Pt 2):549-63.
PMID: 23413263
Loss of the Merlin tumour suppressor causes abnormal de-differentiation and proliferation of Schwann cells and formation of schwannoma tumours in patients with neurofibromatosis type 2. Within the mature peripheral nerve...
4.
Doddrell R, Dun X, Moate R, Jessen K, Mirsky R, Parkinson D
Glia
. 2012 Apr;
60(9):1269-78.
PMID: 22532290
Pax-3 is a paired domain transcription factor that plays many roles during vertebrate development. In the Schwann cell lineage, Pax-3 is expressed at an early stage in Schwann cells precursors...
5.
Parrinello S, Napoli I, Ribeiro S, Wingfield Digby P, Fedorova M, Parkinson D, et al.
Cell
. 2010 Sep;
143(1):145-55.
PMID: 20869108
The peripheral nervous system has astonishing regenerative capabilities in that cut nerves are able to reconnect and re-establish their function. Schwann cells are important players in this process, during which...