Roberto Valverde
Overview
Explore the profile of Roberto Valverde including associated specialties, affiliations and a list of published articles.
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Articles
19
Citations
1022
Followers
0
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Recent Articles
1.
Schonherr H, Ayaz P, Taylor A, Casaletto J, Toure B, Moustakas D, et al.
Proc Natl Acad Sci U S A
. 2024 Feb;
121(6):e2317756121.
PMID: 38300868
Fibroblast growth factor receptor (FGFR) kinase inhibitors have been shown to be effective in the treatment of intrahepatic cholangiocarcinoma and other advanced solid tumors harboring alterations, but the toxicity of...
2.
Varkaris A, Pazolli E, Gunaydin H, Wang Q, Pierce L, Boezio A, et al.
Cancer Discov
. 2023 Nov;
14(2):240-257.
PMID: 37916956
Significance: Treatments for PIK3CA-mutant cancers are limited by toxicities associated with the inhibition of WT PI3Kα. Molecular dynamics, cryo-electron microscopy, and DNA-encoded libraries were used to develop RLY-2608, a first-in-class...
3.
Subbiah V, Sahai V, Maglic D, Bruderek K, Toure B, Zhao S, et al.
Cancer Discov
. 2023 Jun;
13(9):2012-2031.
PMID: 37270847
Significance: Patients with FGFR2-driven cancers derive limited benefit from pan-FGFRi due to multiple FGFR1-4-mediated toxicities and acquired FGFR2 resistance mutations. RLY-4008 is a highly selective FGFR2 inhibitor that targets primary...
4.
Moniche F, Cabezas-Rodriguez J, Valverde R, Escudero-Martinez I, Lebrato-Hernandez L, Pardo-Galiana B, et al.
Lancet Neurol
. 2023 Jan;
22(2):137-146.
PMID: 36681446
Background: Pilot clinical trials have shown the safety of intra-arterial bone marrow mononuclear cells (BMMNCs) in stroke. However, the efficacy of different doses of intra-arterial BMMNCs in patients with acute...
5.
Parms T, Valverde R, Park-Lee E, Graham-Glover B, Cunningham C, Sawdey M, et al.
Addict Behav
. 2022 Nov;
137:107537.
PMID: 36332518
Introduction: Previous studies have indicated that youth who use tobacco products, including cigarettes, cigars, and smokeless tobacco, demonstrate dependence symptoms. However, the tobacco marketplace has expanded dramatically in recent years,...
6.
Gammon D, Rogers T, Coats E, Nonnemaker J, Spinks J, Valverde R, et al.
Am J Prev Med
. 2022 Sep;
63(6):1017-1025.
PMID: 36109309
Introduction: Events during 2019 and 2020, such as the outbreak of e-cigarette, or vaping, product use‒associated lung injury; manufacturer product withdrawals; federal regulations; and coronavirus disease 2019, potentially affected the...
7.
Mancha F, Escudero-Martinez I, Zapata-Arriaza E, Vega-Salvatierra A, Cabezas J, Lebrato L, et al.
J Investig Med
. 2019 Dec;
68(3):807-810.
PMID: 31852749
Previous studies have shown the potential of microRNAs (miRNA) in the pathological process of stroke and functional recovery. Bone marrow mononuclear cell (BM-MNC) transplantation improves recovery in experimental models of...
8.
He Y, Shimizu I, Schappert S, Xu J, Beresovsky V, Khan D, et al.
J Off Stat
. 2019 Apr;
32(1):147-164.
PMID: 30948863
Multiple imputation is a popular approach to handling missing data. Although it was originally motivated by survey nonresponse problems, it has been readily applied to other data settings. However, its...
9.
Jenni S, Dimitrova Y, Valverde R, Hinshaw S, Harrison S
Cold Spring Harb Symp Quant Biol
. 2017 Nov;
82:83-89.
PMID: 29167284
Kinetochore molecular architecture exemplifies "form follows function." The simplifications that generated the one-chromosome:one-microtubule linkage in point-centromere yeast have enabled strategies for systematic structural analysis and high-resolution visualization of many kinetochore...
10.
Dimitrova Y, Jenni S, Valverde R, Khin Y, Harrison S
Cell
. 2016 Nov;
167(4):1014-1027.e12.
PMID: 27881300
Kinetochores connect centromeric nucleosomes with mitotic-spindle microtubules through conserved, cross-interacting protein subassemblies. In budding yeast, the heterotetrameric MIND complex (Mtw1, Nnf1, Nsl1, Dsn1), ortholog of the metazoan Mis12 complex, joins...