Roberta Lucchi
Overview
Explore the profile of Roberta Lucchi including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
77
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Recent Articles
1.
Lucana M, Lucchi R, Gosselet F, Diaz-Perlas C, Oller-Salvia B
RSC Chem Biol
. 2024 Jan;
5(1):7-11.
PMID: 38179197
Protein therapeutics cannot reach the brain in sufficient amounts because of their low permeability across the blood-brain barrier. Here we report a new family of bicyclic peptide shuttles, BrainBikes, capable...
2.
Lucchi R, Lucana M, Escobar-Rosales M, Diaz-Perlas C, Oller-Salvia B
N Biotechnol
. 2023 Oct;
78:76-83.
PMID: 37820830
Antibody therapeutics show great potential to treat a variety of diseases. Often, the dose that can be safely administered is limited by side effects that arise from the interaction with...
3.
Lucana M, Arruga Y, Petrachi E, Roig A, Lucchi R, Oller-Salvia B
Pharmaceutics
. 2021 Dec;
13(12).
PMID: 34959346
Peptides show high promise in the targeting and intracellular delivery of next-generation bio- and nano-therapeutics. However, the proteolytic susceptibility of peptides is one of the major limitations of their activity...
4.
Spizzichino S, Boi D, Boumis G, Lucchi R, Liberati F, Capelli D, et al.
FEBS J
. 2021 Oct;
289(6):1625-1649.
PMID: 34694685
De novo thymidylate synthesis is a crucial pathway for normal and cancer cells. Deoxythymidine monophosphate (dTMP) is synthesized by the combined action of three enzymes: serine hydroxymethyltransferase (SHMT1), dihydrofolate reductase...
5.
Lucchi R, Bentanachs J, Oller-Salvia B
ACS Cent Sci
. 2021 Jun;
7(5):724-738.
PMID: 34079893
The high selectivity and affinity of antibody binding have made antibodies all-pervasive tools in therapy, diagnosis, and basic science. A plethora of chemogenetic approaches has been devised to make antibodies...
6.
Giardina G, Paone A, Tramonti A, Lucchi R, Marani M, Magnifico M, et al.
FEBS J
. 2018 Jul;
285(17):3238-3253.
PMID: 30035852
Database: Structural data are available in the PDB under the accession number 6FL5.