Robert Yan
Overview
Explore the profile of Robert Yan including associated specialties, affiliations and a list of published articles.
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Articles
21
Citations
298
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Recent Articles
1.
Yan R, Rios P, Pastore A, Temussi P
Commun Chem
. 2022 Mar;
1(1).
PMID: 35243006
Proteins undergo both cold and heat denaturation, but often cold denaturation cannot be detected because it occurs at temperatures below water freezing. Proteins undergoing detectable cold as well as heat...
2.
Te Lintel Hekkert M, Newton G, Chapman K, Aqil R, Downham R, Yan R, et al.
Basic Res Cardiol
. 2021 May;
116(1):34.
PMID: 34018053
Reducing infarct size (IS) by interfering with mechanisms for cardiomyocyte death remains an elusive goal. DMX-5804, a selective inhibitor of the stress-activated kinase MAP4K4, suppresses cell death in mouse myocardial...
3.
Golforoush P, Narasimhan P, Chaves-Guerrero P, Lawrence E, Newton G, Yan R, et al.
Sci Rep
. 2020 Jul;
10(1):12060.
PMID: 32694738
Given the poor track record to date of animal models for creating cardioprotective drugs, human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) have been proposed as a therapeutically relevant human platform to...
4.
Fiedler L, Chapman K, Xie M, Maifoshie E, Jenkins M, Golforoush P, et al.
Cell Stem Cell
. 2020 Mar;
26(3):458.
PMID: 32142664
No abstract available.
5.
Kaul S, Wojno K, Stone S, Evans B, Bernhisel R, Meek S, et al.
Per Med
. 2019 Sep;
16(6):491-499.
PMID: 31483217
To evaluate active surveillance (AS) selection, safety and durability among men with low-risk prostate cancer assessed using the clinical cell cycle risk (CCR) score, a combined clinical and molecular score....
6.
Fiedler L, Chapman K, Xie M, Maifoshie E, Jenkins M, Golforoush P, et al.
Cell Stem Cell
. 2019 Mar;
24(4):579-591.e12.
PMID: 30853557
Heart disease is a paramount cause of global death and disability. Although cardiomyocyte death plays a causal role and its suppression would be logical, no clinical counter-measures target the responsible...
7.
Rasheed M, Jamshidiha M, Puglisi R, Yan R, Cota E, Pastore A
FEBS J
. 2019 Jan;
286(3):495-506.
PMID: 30636112
Frataxins form an interesting family of iron-binding proteins with an almost unique fold and are highly conserved from bacteria to primates. They have a pivotal role in iron-sulfur cluster biogenesis...
8.
Yan R, Yalinca H, Paoletti F, Gobbo F, Marchetti L, Kuzmanic A, et al.
Structure
. 2018 Nov;
27(1):78-89.e3.
PMID: 30393051
Nerve growth factor (NGF) is an important neurotrophic factor involved in the regulation of cell differentiation and survival of target neurons. Expressed as a proNGF precursor, NGF is matured by...
9.
Rasheed M, Yan R, Kelly G, Pastore A
Biomol NMR Assign
. 2017 Nov;
12(1):113-116.
PMID: 29090418
Frataxin is the protein responsible for the genetically-inherited neurodegenerative disease Friedreich's ataxia caused by partial silencing of the protein and loss of function. Although the frataxin function is not yet...
10.
Paoletti F, de Chiara C, Kelly G, Covaceuszach S, Malerba F, Yan R, et al.
Front Mol Biosci
. 2017 Jan;
3:83.
PMID: 28083536
Nerve Growth Factor (NGF), the prototype of the neurotrophin family, is essential for maintenance and growth of different neuronal populations. The X-ray crystal structure of NGF has been known since...