Robert Wattiaux
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Explore the profile of Robert Wattiaux including associated specialties, affiliations and a list of published articles.
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7
Citations
63
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Recent Articles
1.
Gasingirwa M, Thirion J, Mertens-Strijthagen J, Wattiaux-De Coninck S, Flamion B, Wattiaux R, et al.
Biochem J
. 2010 Jun;
430(2):305-13.
PMID: 20572808
It has been suggested that intracellular Hyal-1 (hyaluronidase-1), which is considered a lysosomal enzyme, originates via endocytosis of the serum enzyme. To test this proposal we have investigated the uptake...
2.
Wattiaux R, Wattiaux-De Coninck S, Thirion J, Gasingirwa M, Jadot M
Biochem J
. 2006 Nov;
403(1):89-95.
PMID: 17129211
A number of studies, mostly performed ex vivo, suggest that lysosomes are involved in apoptosis as a result of a release of their cathepsins into the cytosol. These enzymes could...
3.
Andrianaivo F, Lecocq M, Wattiaux-De Coninck S, Wattiaux R, Jadot M
J Gene Med
. 2004 Aug;
6(8):877-83.
PMID: 15293346
Background: The mechanism of gene transfer into hepatocytes by the hydrodynamics-based transfection procedure is not clearly understood. It has been shown that, after a hydrodynamic injection, a large proportion of...
4.
Colaco M, Misquith S, Bapat M, Wattiaux-De Coninck S, Wattiaux R
Biochem Biophys Res Commun
. 2004 Jun;
319(4):1299-306.
PMID: 15194509
Intravenous injection of gelonin and deglycosylated gelonin led to rapid clearance from the blood. Both molecules distributed similarly in liver and kidney suggesting that they followed the same pathway. Deglycosylation...
5.
Thirion J, Wattiaux R, Jadot M
Biol Cell
. 2003 Jun;
95(2):99-105.
PMID: 12799065
We found a dipeptidyl aminopeptidase activity in the parasitic protozoan Giardia lamblia with properties similar to the lysosomal cathepsin C of rat-liver lysosomes. Subcellular fractionation of this parasite indicated that...
6.
Lecocq M, Andrianaivo F, Warnier M, Wattiaux-De Coninck S, Wattiaux R, Jadot M
J Gene Med
. 2003 Jan;
5(2):142-56.
PMID: 12539152
Background: An efficient gene transfer can be achieved in mouse liver by a rapid tail vein injection of a large volume of plasmid DNA solution (hydrodynamics-based transfection). The mechanism of...
7.
Colaco M, Bapat M, Misquith S, Jadot M, Wattiaux-De Coninck S, Wattiaux R
Biochem Biophys Res Commun
. 2002 Sep;
296(5):1180-5.
PMID: 12207898
Gelonin, a type 1 ribosome-inactivating protein, has been used as toxin conjugate for several therapeutic purposes. We have investigated the endocytosis of gelonin by rat liver in vivo. Subcellular distribution...