Robert Steen
Overview
Explore the profile of Robert Steen including associated specialties, affiliations and a list of published articles.
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10
Citations
469
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Recent Articles
1.
Ashton J, Rehrauer H, Myers J, Myers J, Zanche M, Balys M, et al.
J Biomol Tech
. 2022 Jul;
32(4).
PMID: 35837267
Single-cell RNA sequencing (scRNA-seq) offers great new opportunities for increasing our understanding of complex biological processes. In particular, development of an accurate Human Cell Atlas is largely dependent on the...
2.
Forgetta V, Leveque G, Dias J, Grove D, Lyons Jr R, Genik S, et al.
J Biomol Tech
. 2013 Apr;
24(1):39-49.
PMID: 23542132
As part of the DNA Sequencing Research Group of the Association of Biomolecular Resource Facilities, we have tested the reproducibility of the Roche/454 GS-FLX Titanium System at five core facilities....
3.
Asmal M, Whitney J, Luedemann C, Carville A, Steen R, Letvin N, et al.
PLoS One
. 2012 Nov;
7(11):e48234.
PMID: 23133620
Endogenous serine protease inhibitors (serpins) are anti-inflammatory mediators with multiple biologic functions. Several serpins have been reported to modulate HIV pathogenesis, or exhibit potent anti-HIV activity in vitro, but the...
4.
Steglich C, Lindell D, Futschik M, Rector T, Steen R, Chisholm S
Genome Biol
. 2010 May;
11(5):R54.
PMID: 20482874
Background: RNA turnover plays an important role in the gene regulation of microorganisms and influences their speed of acclimation to environmental changes. We investigated whole-genome RNA stability of Prochlorococcus, a...
5.
Osburne M, Holmbeck B, Frias-Lopez J, Steen R, Huang K, Kelly L, et al.
Environ Microbiol
. 2010 Mar;
12(7):1978-88.
PMID: 20345942
Exposure to solar radiation can cause mortality in natural communities of pico-phytoplankton, both at the surface and to a depth of at least 30 m. DNA damage is a significant...
6.
Kieleczawa J, Adam D, Bintzler D, Detwiler M, Needleman D, Schweitzer P, et al.
J Biomol Tech
. 2009 Jun;
20(2):116-27.
PMID: 19503623
The 2008 ABRF DNA Sequencing Research Group (DSRG) difficult template sequencing study was designed to identify a general set of guidelines that would constitute the best approaches for sequencing difficult...
7.
Zinser E, Lindell D, Johnson Z, Futschik M, Steglich C, Coleman M, et al.
PLoS One
. 2009 Apr;
4(4):e5135.
PMID: 19352512
The marine cyanobacterium Prochlorococcus MED4 has the smallest genome and cell size of all known photosynthetic organisms. Like all phototrophs at temperate latitudes, it experiences predictable daily variation in available...
8.
Lindell D, Jaffe J, Coleman M, Futschik M, Axmann I, Rector T, et al.
Nature
. 2007 Sep;
449(7158):83-6.
PMID: 17805294
Interactions between bacterial hosts and their viruses (phages) lead to reciprocal genome evolution through a dynamic co-evolutionary process. Phage-mediated transfer of host genes--often located in genome islands--has had a major...
9.
Tolonen A, Aach J, Lindell D, Johnson Z, Rector T, Steen R, et al.
Mol Syst Biol
. 2006 Oct;
2:53.
PMID: 17016519
Nitrogen (N) often limits biological productivity in the oceanic gyres where Prochlorococcus is the most abundant photosynthetic organism. The Prochlorococcus community is composed of strains, such as MED4 and MIT9313,...
10.
Steglich C, Futschik M, Rector T, Steen R, Chisholm S
J Bacteriol
. 2006 Sep;
188(22):7796-806.
PMID: 16980454
Prochlorococcus MED4 has, with a total of only 1,716 annotated protein-coding genes, the most compact genome of a free-living photoautotroph. Although light quality and quantity play an important role in...