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Robert Silbergleit

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Articles 123
Citations 2308
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Schmitzberger F, Fowler J, Hsu C, Pai M, Neumar R, Meurer W, et al.
Clin Transl Sci . 2024 Nov; 17(11):e70071. PMID: 39558506
Intranasal insulin is a putative neuroprotective therapy after cardiac arrest, but safety in humans at doses extrapolated from animal models is unknown. This phase I, open-label adaptive dose-escalation study explores...
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Beekman R, Perman S, Nguyen C, Kline P, Clevenger R, Yeatts S, et al.
Resuscitation . 2024 Sep; 203:110397. PMID: 39278393
Aim: Temperature control is a complex bundled intervention; the synergistic impact of each individual component is ill defined and underreported. Resultantly, the influence of parameter optimization on temperature control's overall...
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Meurer W, Schmitzberger F, Yeatts S, Ramakrishnan V, Abella B, Aufderheide T, et al.
Trials . 2024 Jul; 25(1):502. PMID: 39044295
Background: Cardiac arrest is a common and devastating emergency of both the heart and brain. More than 380,000 patients suffer out-of-hospital cardiac arrest annually in the USA. Induced cooling of...
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Meurer W, Schmitzberger F, Yeatts S, Ramakrishnan V, Abella B, Aufderheide T, et al.
Res Sq . 2024 Jul; PMID: 38947064
Background: Cardiac arrest is a common and devastating emergency of both the heart and brain. More than 380,000 patients suffer out-of-hospital cardiac arrest annually in the United States. Induced cooling...
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Shi X, Wick J, Martin R, Beall J, Silbergleit R, Rockswold G, et al.
Stat Med . 2024 Jun; 43(19):3649-3663. PMID: 38885949
Emergency medical diseases (EMDs) are the leading cause of death worldwide. A time-to-death analysis is needed to accurately identify the risks and describe the pattern of an EMD because the...
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Steinberg A, Yang Y, Fischhoff B, Callaway C, Coppler P, Geocadin R, et al.
Resuscitation . 2024 Apr; 199:110226. PMID: 38685376
Purpose: Perceived poor prognosis can lead to withdrawal of life-sustaining therapies (WLST) in patients who might otherwise recover. We characterized clinicians' approach to post-arrest prognostication in a multicenter clinical trial....
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Diaz-Arrastia R, Bernard F, Shutter L, Barsan W, Silbergleit R
Lancet Neurol . 2024 Feb; 23(3):230-231. PMID: 38365369
No abstract available.
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Guetterman T, Haggins A, Montas S, Black J, Harney D, Fetters M, et al.
Ethics Hum Res . 2024 Jan; 46(1):2-13. PMID: 38240398
The nature of the review of local context by institutional review boards (IRBs) is vague. Requirements for single IRB review of multicenter trials create a need to better understand interpretation...
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Wang Y, Yeatts S, Martin R, Silbergleit R, Rockswold G, Barsan W, et al.
Stat Med . 2023 Aug; 42(25):4582-4601. PMID: 37599009
The Glasgow outcome scale-extended (GOS-E), an ordinal scale measure, is often selected as the endpoint for clinical trials of traumatic brain injury (TBI). Traditionally, GOS-E is analyzed as a fixed...