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Robert Pajdo

Explore the profile of Robert Pajdo including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 28
Citations 427
Followers 0
Related Specialties
Pharmacology
Gastroenterology
Biochemistry
Top 10 Co-Authors
Tomasz Brzozowski
Slawomir Kwiecien
Stanislaw J Konturek
Danuta Drozdowicz
Peter C Konturek
Zbigniew Sliwowski
Wieslaw W Pawlik
Marcin Magierowski
Eckhart G Hahn
Katarzyna Magierowska
Published In
Curr Pharm Des
J Pharmacol Exp Ther
Eur J Pharmacol
J Gastroenterol
Cells
Affiliations
Soon will be listed here.
Recent Articles
1.
Evidence for Cytoprotective Effect of Carbon Monoxide Donor in the Development of Acute Esophagitis Leading to Acute Esophageal Epithelium Lesions
Magierowska K, Bakalarz D, Wojcik D, Korbut E, Danielak A, Glowacka U, et al.
Cells . 2020 May; 9(5). PMID: 32408627
Exposure to acidic gastric content due to malfunction of lower esophageal sphincter leads to acute reflux esophagitis (RE) leading to disruption of esophageal epithelial cells. Carbon monoxide (CO) produced by...
2.
Alternative Therapy in the Prevention of Experimental and Clinical Inflammatory Bowel Disease. Impact of Regular Physical Activity, Intestinal Alkaline Phosphatase and Herbal Products
Bilski J, Wojcik D, Danielak A, Mazur-Bialy A, Magierowski M, Tonnesen K, et al.
Curr Pharm Des . 2020 Apr; 26(25):2936-2950. PMID: 32338209
Inflammatory bowel diseases (IBD), such as ulcerative colitis and Crohn's disease, are multifactorial, chronic, disabling, and progressive diseases characterised by cyclical nature, alternating between active and quiescent states. While the...
3.
Role of Obesity, Mesenteric Adipose Tissue, and Adipokines in Inflammatory Bowel Diseases
Bilski J, Mazur-Bialy A, Wojcik D, Surmiak M, Magierowski M, Sliwowski Z, et al.
Biomolecules . 2019 Nov; 9(12). PMID: 31779136
Inflammatory bowel diseases (IBDs) are a group of disorders which include ulcerative colitis and Crohn's disease. Obesity is becoming increasingly more common among patients with inflammatory bowel disease and plays...
4.
Mouse model of gastric infection with cytotoxin-expressing strain of Helicobacter pylori in studying of pathogenesis of chronic gastric ulcer
Konturek P, Brzozowski T, Konturek S, Karczewska E, Pajdo R, Ghiara P, et al.
J Gastroenterol Hepatol . 2017 Oct; 13(S3):S178-S184. PMID: 28976668
Helicobacter pylori is a major risk factor for peptic ulcer, but studies on the role of H. pylori infection in gastric pathology are limited due to lack of convenient models...
5.
Mechanisms of curcumin-induced gastroprotection against ethanol-induced gastric mucosal lesions
Czekaj R, Majka J, Magierowska K, Sliwowski Z, Magierowski M, Pajdo R, et al.
J Gastroenterol . 2017 Sep; 53(5):618-630. PMID: 28856444
Background: Curcumin, a pleiotropic substance used for centuries in traditional medicine, exhibits antioxidant, anti-inflammatory and antiproliferative efficacy against various tumours, but the role of curcumin in gastroprotection is little studied....
6.
Carbon monoxide released from its pharmacological donor, tricarbonyldichlororuthenium (II) dimer, accelerates the healing of pre-existing gastric ulcers
Magierowski M, Magierowska K, Hubalewska-Mazgaj M, Sliwowski Z, Ginter G, Pajdo R, et al.
Br J Pharmacol . 2017 Aug; 174(20):3654-3668. PMID: 28768046
Background And Purpose: Carbon monoxide (CO), a gaseous mediator produced by haem oxygenases (HOs), has been shown to prevent stress-, ethanol-, aspirin- and alendronate-induced gastric damage; however, its role in...
7.
Recent Advances in the Gastric Mucosal Protection Against Stress-induced Gastric Lesions. Importance of Renin-angiotensin Vasoactive Metabolites, Gaseous Mediators and Appetite Peptides
Brzozowski T, Magierowska K, Magierowski M, Ptak-Belowska A, Pajdo R, Kwiecien S, et al.
Curr Pharm Des . 2017 Feb; 23(27):3910-3922. PMID: 28228069
Stress is known to cause severe adverse effects in the human gastrointestinal tract including mucosal microbleedings and erosions or even gastric ulceration but the mechanism of these complications has not...
8.
Exogenous and Endogenous Hydrogen Sulfide Protects Gastric Mucosa against the Formation and Time-Dependent Development of Ischemia/Reperfusion-Induced Acute Lesions Progressing into Deeper Ulcerations
Magierowski M, Magierowska K, Hubalewska-Mazgaj M, Sliwowski Z, Pajdo R, Ginter G, et al.
Molecules . 2017 Feb; 22(2). PMID: 28212299
Hydrogen sulfide (H₂S) is an endogenous mediator, synthesized from l-cysteine by cystathionine γ-lyase (CSE), cystathionine β-synthase (CBS) or 3-mercaptopyruvate sulfurtransferase (3-MST). The mechanism(s) involved in H₂S-gastroprotection against ischemia/reperfusion (I/R) lesions...
9.
Interaction between endogenous carbon monoxide and hydrogen sulfide in the mechanism of gastroprotection against acute aspirin-induced gastric damage
Magierowski M, Magierowska K, Hubalewska-Mazgaj M, Adamski J, Bakalarz D, Sliwowski Z, et al.
Pharmacol Res . 2016 Nov; 114:235-250. PMID: 27825819
Acetylsalicylic acid (ASA) is mainly recognized as painkiller or anti-inflammatory drug. However, ASA causes serious side effects towards gastrointestinal (GI) tract which limits its usefulness. Carbon monoxide (CO) and hydrogen...
10.
Mechanisms by which Stress Affects the Experimental and Clinical Inflammatory Bowel Disease (IBD): Role of Brain-Gut Axis
Brzozowski B, Mazur-Bialy A, Pajdo R, Kwiecien S, Bilski J, Zwolinska-Wcislo M, et al.
Curr Neuropharmacol . 2016 Apr; 14(8):892-900. PMID: 27040468
Background: Stress of different origin is known to alter so called "braingut axis" and contributes to a broad array of gastrointestinal disorders including inflammatory bowel disease (IBD), irritable bowel syndrome...