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Robert P Rambo

Explore the profile of Robert P Rambo including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Spiteri V, Doutch J, Rambo R, Bhatt J, Gor J, Dalby P, et al.
PLoS One . 2024 Apr; 19(4):e0300964. PMID: 38557973
Human immunoglobulin G (IgG) exists as four subclasses IgG1-4, each of which has two Fab subunits joined by two hinges to a Fc subunit. IgG4 has the shortest hinge with...
2.
Walters L, Rozbesky D, Harlos K, Quastel M, Sun H, Springer S, et al.
Cell Rep . 2022 Jun; 39(11):110959. PMID: 35705051
MHC-E regulates NK cells by displaying MHC class Ia signal peptides (VL9) to NKG2A:CD94 receptors. MHC-E can also present sequence-diverse, lower-affinity, pathogen-derived peptides to T cell receptors (TCRs) on CD8...
3.
Spiteri V, Goodall M, Doutch J, Rambo R, Gor J, Perkins S
J Biol Chem . 2021 Jul; 297(3):100995. PMID: 34302810
Human immunoglobulin G subclass 3 (IgG3) possesses a uniquely long hinge region that separates its Fab antigen-binding and Fc receptor-binding regions. Owing to this hinge length, the molecular structure of...
4.
Spiteri V, Doutch J, Rambo R, Gor J, Dalby P, Perkins S
Biophys J . 2021 Mar; 120(9):1814-1834. PMID: 33675758
The human immunoglobulin G (IgG) class is the most prevalent antibody in serum, with the IgG1 subclass being the most abundant. IgG1 is composed of two Fab regions connected to...
5.
Tully M, Tarbouriech N, Rambo R, Hutin S
J Vis Exp . 2021 Feb; (167). PMID: 33586708
BioSAXS is a popular technique used in molecular and structural biology to determine the solution structure, particle size and shape, surface-to-volume ratio and conformational changes of macromolecules and macromolecular complexes....
6.
Le Vay K, Carter B, Watkins D, Tang T, Ting V, Colfen H, et al.
J Am Chem Soc . 2020 Nov; 142(49):20640-20650. PMID: 33252237
Controlling the assembly and disassembly of nanoscale protein cages for the capture and internalization of protein or non-proteinaceous components is fundamentally important to a diverse range of bionanotechnological applications. Here,...
7.
Cowieson N, Edwards-Gayle C, Inoue K, Khunti N, Doutch J, Williams E, et al.
J Synchrotron Radiat . 2020 Sep; 27(Pt 5):1438-1446. PMID: 32876621
B21 is a small-angle X-ray scattering (SAXS) beamline with a bending magnet source in the 3 GeV storage ring at the Diamond Light Source Ltd synchrotron in the UK. The...
8.
Imamura A, Okada T, Mase H, Otani T, Kobayashi T, Tamura M, et al.
Nat Commun . 2020 Apr; 11(1):1837. PMID: 32296055
Guanosine 5'-monophosphate reductase (GMPR) is involved in the purine salvage pathway and is conserved throughout evolution. Nonetheless, the GMPR of Trypanosoma brucei (TbGMPR) includes a unique structure known as the...
9.
Yeh V, Goode A, Eastham G, Rambo R, Inoue K, Doutch J, et al.
Langmuir . 2020 Mar; 36(33):9649-9657. PMID: 32202793
Bioproduction of poly(methyl methacrylate) is a fast growing global industry that is limited by cellular toxicity of monomeric methacrylate intermediates to the producer strains. Maintaining high methacrylate concentrations during biofermentation,...
10.
Edwards-Gayle C, Castelletto V, Hamley I, Barrett G, Greco F, Hermida-Merino D, et al.
ACS Appl Bio Mater . 2019 Jun; 2(5):2208-2218. PMID: 31157325
The self-assembly and antimicrobial activity of two novel arginine-capped bola-amphiphile peptides, namely RAR and RAR (R, arginine; A, alanine) are investigated. RAR does not self-assemble in water due to its...