Robert M Nissen
Overview
Explore the profile of Robert M Nissen including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
9
Citations
904
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Yousefelahiyeh M, Xu J, Alvarado E, Yu Y, Salven D, Nissen R
PLoS One
. 2018 Nov;
13(11):e0207779.
PMID: 30496304
Overexpression of the Dual-specificity Tyrosine Phosphorylation-Regulated Kinase 1A (DYRK1A) gene contributes to the retardation, craniofacial anomalies, cognitive impairment, and learning and memory deficits associated with Down Syndrome (DS). DCAF7/HAN11/WDR68 (hereafter...
2.
Alvarado E, Yousefelahiyeh M, Alvarado G, Shang R, Whitman T, Martinez A, et al.
PLoS One
. 2016 Nov;
11(11):e0166984.
PMID: 27880803
Birth defects are among the leading causes of infant mortality and contribute substantially to illness and long-term disability. Defects in Bone Morphogenetic Protein (BMP) signaling are associated with cleft lip/palate....
3.
Wang B, Doan D, Roman Petersen Y, Alvarado E, Alvarado G, Bhandari A, et al.
PLoS One
. 2013 Jan;
8(1):e54363.
PMID: 23349862
Wdr68 is a highly conserved scaffolding protein required for craniofacial development and left-right asymmetry. A Ras-Map3k-Wdr68-Dyrk1 signaling relay may mediate these and other diverse signaling events important in development and...
4.
Mazmanian G, Kovshilovsky M, Yen D, Mohanty A, Mohanty S, Nee A, et al.
Genesis
. 2009 Dec;
48(1):20-30.
PMID: 20014342
Nodal-signaling is required for specification of mesoderm, endoderm, establishing left-right asymmetry, and craniofacial development. Wdr68 is a WD40-repeat domain-containing protein recently shown to be required for endothelin-1 (edn1) expression and...
5.
Nissen R, Amsterdam A, Hopkins N
BMC Dev Biol
. 2006 Jun;
6:28.
PMID: 16759393
Background: Craniofacial birth defects result from defects in cranial neural crest (NC) patterning and morphogenesis. The vertebrate craniofacial skeleton is derived from cranial NC cells and the patterning of these...
6.
Amsterdam A, Nissen R, Sun Z, Swindell E, Farrington S, Hopkins N
Proc Natl Acad Sci U S A
. 2004 Jul;
101(35):12792-7.
PMID: 15256591
We completed a large insertional mutagenesis screen in zebrafish to identify genes essential for embryonic and early larval development. We isolated 525 mutants, representing lesions in approximately 390 different genes,...
7.
Nissen R, Yan J, Amsterdam A, Hopkins N, Burgess S
Development
. 2003 Apr;
130(11):2543-54.
PMID: 12702667
We identified four insertional alleles of foxi one (foo), an embryonic lethal mutation in zebrafish that displays defects in both otic placode and the jaw. In foo/foo embryos the otic...
8.
Yan Y, Miller C, Nissen R, Singer A, Liu D, Kirn A, et al.
Development
. 2002 Oct;
129(21):5065-79.
PMID: 12397114
The molecular genetic mechanisms of cartilage construction are incompletely understood. Zebrafish embryos homozygous for jellyfish (jef) mutations show craniofacial defects and lack cartilage elements of the neurocranium, pharyngeal arches, and...
9.
Golling G, Amsterdam A, Sun Z, Antonelli M, Maldonado E, Chen W, et al.
Nat Genet
. 2002 May;
31(2):135-40.
PMID: 12006978
To rapidly identify genes required for early vertebrate development, we are carrying out a large-scale, insertional mutagenesis screen in zebrafish, using mouse retroviral vectors as the mutagen. We will obtain...