Robert L Rodgers
Overview
Explore the profile of Robert L Rodgers including associated specialties, affiliations and a list of published articles.
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8
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44
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Recent Articles
1.
Rodgers R
Peptides
. 2022 Nov;
159:170906.
PMID: 36396082
Effects of the metabolic hormone glucagon can be physiological or supraphysiological, based on agonist concentration and the mediating cellular signal. The threshold concentration (TC) for activating the AC/cAMP signal pathway...
2.
Rodgers R
Physiol Rep
. 2022 May;
10(9):e15263.
PMID: 35569125
For at least 50 years, the prevailing view has been that the adenylate cyclase (AC)/cyclic AMP (cAMP)/protein kinase A pathway is the predominant signal mediating the hepatic glucose-mobilizing actions of...
3.
Rodgers R
Am J Physiol Endocrinol Metab
. 2021 Aug;
321(4):E580.
PMID: 34369822
No abstract available.
4.
Rodgers R
Am J Physiol Endocrinol Metab
. 2021 Jul;
321(4):E575-E578.
PMID: 34280050
No abstract available.
5.
Rodgers R
Curr Diabetes Rev
. 2012 May;
8(5):362-81.
PMID: 22587514
It is well established that glucagon can stimulate adipose lipolysis, myocardial contractility, and hepatic glucose output by activating a GPCR and adenylate cyclase (AC) and increasing cAMP production. It is...
6.
Dunn M, Manfredi T, Cosmas A, Vetter F, King J, Rodgers R
Cardiovasc Pathol
. 2011 Feb;
20(6):343-51.
PMID: 21296006
Background: Glycolytic flux in the mouse heart during the progression of left ventricular hypertrophy (LVH) and mechanical dysfunction has not been described. Methods: The main objectives of this study were...
7.
Harney J, Rodgers R
Am J Physiol Endocrinol Metab
. 2008 May;
295(1):E155-61.
PMID: 18492769
At concentrations around 10(-9) M or higher, glucagon increases cardiac contractility by activating adenylate cyclase/cyclic adenosine monophosphate (AC/cAMP). However, blood levels in vivo, in rats or humans, rarely exceed 10(-10)...
8.
Daniels T, Gallagher M, Tremblay G, Rodgers R
Can J Physiol Pharmacol
. 2004 Dec;
82(10):927-33.
PMID: 15573154
We investigated whether the antiepileptic valproic acid (VPA) might interfere with oxidative metabolism in heart, as it does in liver. We administered VPA to working rat hearts perfused with radiolabeled...