Robert L Raffai
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Explore the profile of Robert L Raffai including associated specialties, affiliations and a list of published articles.
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59
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7026
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Recent Articles
11.
LaPlante E, Sturchler A, Fullem R, Chen D, Starner A, Esquivel E, et al.
Cell Genom
. 2023 May;
3(5):100303.
PMID: 37228754
Although the role of RNA binding proteins (RBPs) in extracellular RNA (exRNA) biology is well established, their exRNA cargo and distribution across biofluids are largely unknown. To address this gap,...
12.
Lopez J, Ramirez J, Phu T, Duong P, Bouchareychas L, Kuhrau C, et al.
PLoS One
. 2023 Feb;
18(2):e0281371.
PMID: 36787323
Objective: There are currently no specific biomarkers to identify patients with abdominal aortic aneurysms (AAAs). Circulating exosomes contain microRNAs (miRNA) that are potential biomarkers for the presence of disease. This...
13.
Li G, Chen T, Dahlman J, Eniola-Adefeso L, Ghiran I, Kurre P, et al.
J Extracell Vesicles
. 2023 Feb;
12(2):e12305.
PMID: 36775986
Extracellular vesicles (EVs) carry diverse bioactive components including nucleic acids, proteins, lipids and metabolites that play versatile roles in intercellular and interorgan communication. The capability to modulate their stability, tissue-specific...
14.
Reitz K, Althouse A, Forman D, Zuckerbraun B, Vodovotz Y, Zamora R, et al.
BMC Cardiovasc Disord
. 2023 Jan;
23(1):38.
PMID: 36681798
Background: Peripheral artery disease (PAD) affects over 230 million people worldwide and is due to systemic atherosclerosis with etiology linked to chronic inflammation, hypertension, and smoking status. PAD is associated...
15.
Mateescu B, Jones J, Alexander R, Alsop E, An J, Asghari M, et al.
iScience
. 2022 Aug;
25(8):104653.
PMID: 35958027
The extracellular RNA communication consortium (ERCC) is an NIH-funded program aiming to promote the development of new technologies, resources, and knowledge about exRNAs and their carriers. After Phase 1 (2013-2018),...
16.
Davies M, Garcia S, Liu M, Chi H, Kim H, Raffai R, et al.
Am J Sports Med
. 2022 May;
50(8):2247-2257.
PMID: 35604307
Background: Muscle atrophy, fibrosis, and fatty infiltration are common to a variety of sports-related and degenerative conditions and are thought to be irreversible. Fibroadipogenic progenitors (FAPs) are multipotent resident muscle...
17.
Phu T, Ng M, Vu N, Bouchareychas L, Raffai R
Mol Ther
. 2022 Mar;
30(6):2274-2297.
PMID: 35292359
Cardiometabolic disease is an increasing cause of morbidity and death in society. While M1-like macrophages contribute to metabolic inflammation and insulin resistance, those polarized to an M2-like phenotype exert protective...
18.
Bittel M, Reichert P, Sarfati I, Dressel A, Leikam S, Uderhardt S, et al.
J Extracell Vesicles
. 2021 Oct;
10(12):e12159.
PMID: 34664784
The intestinal microbiota influences mammalian host physiology in health and disease locally in the gut but also in organs devoid of direct contact with bacteria such as the liver and...
19.
Bouchareychas L, Duong P, Phu T, Alsop E, Meechoovet B, Reiman R, et al.
iScience
. 2021 Aug;
24(8):102847.
PMID: 34381972
We investigated whether extracellular vesicles (EVs) produced under hyperglycemic conditions could communicate signaling to drive atherosclerosis. We did so by treating Apoe mice with exosomes produced by bone marrow-derived macrophages...
20.
Duong P, Chung A, Bouchareychas L, Raffai R
PLoS One
. 2020 Jul;
15(7):e0236914.
PMID: 32702013
[This corrects the article DOI: 10.1371/journal.pone.0215324.].