Robert L J Graham
Overview
Explore the profile of Robert L J Graham including associated specialties, affiliations and a list of published articles.
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27
Citations
1150
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0
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Recent Articles
1.
Irvine A, McKenzie D, McCoy C, Graham R, Graham C, Huws S, et al.
PLoS Pathog
. 2023 Jul;
19(7):e1011508.
PMID: 37523405
Antimicrobial Peptides (AMPs) are immune effectors that are key components of the invertebrate innate immune system providing protection against pathogenic microbes. Parasitic helminths (phylum Nematoda and phylum Platyhelminthes) share complex...
2.
Ulanga U, Russell M, Patassini S, Brazzatti J, Graham C, Whetton A, et al.
Sci Data
. 2021 Apr;
8(1):118.
PMID: 33903600
Murine models are amongst the most widely used systems to study biology and pathology. Targeted quantitative proteomic analysis is a relatively new tool to interrogate such systems. Recently the need...
3.
Varuzhanyan G, Rojansky R, Sweredoski M, Graham R, Hess S, Ladinsky M, et al.
Elife
. 2019 Oct;
8.
PMID: 31596236
Differentiating cells tailor their metabolism to fulfill their specialized functions. We examined whether mitochondrial fusion is important for metabolic tailoring during spermatogenesis. Acutely after depletion of mitofusins and , spermatogenesis...
4.
Russell M, Graham C, DAmato A, Gentry-Maharaj A, Ryan A, Kalsi J, et al.
Br J Cancer
. 2019 Aug;
121(6):483-489.
PMID: 31388184
Background: An early detection tool for EOC was constructed from analysis of biomarker expression data from serum collected during the UKCTOCS. Methods: This study included 49 EOC cases (19 Type...
5.
Russell M, Graham C, DAmato A, Gentry-Maharaj A, Ryan A, Kalsi J, et al.
Br J Cancer
. 2017 Jul;
117(5):666-674.
PMID: 28664912
Background: There is an urgent need for biomarkers for the early detection of ovarian cancer (OC). The purpose of this study was to assess whether changes in serum levels of...
6.
Russell M, DAmato A, Graham C, Crosbie E, Gentry-Maharaj A, Ryan A, et al.
Oncotarget
. 2016 Dec;
8(1):785-797.
PMID: 27903971
Purpose: Ovarian cancer (OC) is the most lethal gynaecological cancer. Early detection is required to improve patient survival. Risk estimation models were constructed for Type I (Model I) and Type...
7.
Russell M, Walker M, Williamson A, Gentry-Maharaj A, Ryan A, Kalsi J, et al.
Int J Cancer
. 2016 Jan;
138(12):2984-92.
PMID: 26815306
Ovarian cancer (OC) has the highest mortality of all gynaecological cancers. Early diagnosis offers an approach to achieving better outcomes. We conducted a blinded-evaluation of prospectively collected preclinical serum from...
8.
Yuet K, Doma M, Ngo J, Sweredoski M, Graham R, Moradian A, et al.
Proc Natl Acad Sci U S A
. 2015 Feb;
112(9):2705-10.
PMID: 25691744
Proteomic analysis of rare cells in heterogeneous environments presents difficult challenges. Systematic methods are needed to enrich, identify, and quantify proteins expressed in specific cells in complex biological systems including...
9.
Ternan N, Jain S, Graham R, McMullan G
PLoS One
. 2014 Mar;
9(2):e88960.
PMID: 24586458
Clostridium difficile is considered to be the most frequent cause of infectious bacterial diarrhoea in hospitals worldwide yet its adaptive ability remains relatively uncharacterised. Here, we used GeLC/MS and the...
10.
Honarpour N, Rose C, Brumbaugh J, Anderson J, Graham R, Sweredoski M, et al.
Mol Cell Proteomics
. 2014 Jan;
13(3):780-91.
PMID: 24390425
The programmed formation of specific tissues from embryonic stem cells is a major goal of regenerative medicine. To identify points of intervention in cardiac tissue formation, we performed an siRNA...