Robert L Chow
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Explore the profile of Robert L Chow including associated specialties, affiliations and a list of published articles.
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28
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564
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Recent Articles
1.
Kalani L, Kim B, de Chavez A, Roemer A, Mikhailov A, Merritt J, et al.
Hum Mol Genet
. 2024 Aug;
33(21):1833-1845.
PMID: 39137370
Mutations in methyl-CpG binding protein 2 (MeCP2), such as the T158M, P152R, R294X, and R306C mutations, are responsible for most Rett syndrome (RTT) cases. These mutations often result in altered...
2.
Gatti D, Gauthier C, Moeller B, FitzPatrick R, Kennedy M, Pluzhnikova V, et al.
J Leukoc Biol
. 2023 May;
114(3):223-236.
PMID: 37227004
Eosinophils are present in the thymus of mammals, yet their function at this site during homeostatic development is unknown. We used flow cytometry to determine the abundance and phenotype of...
3.
Gulka S, Gowen B, Litke A, Delaney K, Chow R
Front Immunol
. 2023 Feb;
14:1050594.
PMID: 36814930
The corneal epithelium is continuously subjected to external stimuli that results in varying degrees of cellular damage. The use of live-cell imaging approaches has facilitated understanding of the cellular and...
4.
Mesa-Perez M, Hamilton P, Miranda A, Brodie N, OSullivan C, Christie J, et al.
Nucleic Acids Res
. 2022 Feb;
50(3):1620-1638.
PMID: 35104878
The life of RNA polymerase II (RNAPII) transcripts is shaped by the dynamic formation of mutually exclusive ribonucleoprotein complexes (RNPs) that direct transcript biogenesis and turnover. A key regulator of...
5.
Waldner D, Ito K, Chen L, Nguyen L, Chow R, Lee A, et al.
Transl Vis Sci Technol
. 2020 Oct;
9(11):19.
PMID: 33117610
Purpose: Congenital stationary night blindness 2A (CSNB2A) is a genetic retinal disorder characterized by poor visual acuity, nystagmus, strabismus, and other signs of retinal dysfunction resulting from mutations in the...
6.
Debrulle S, Baudouin C, Hidalgo-Figueroa M, Pelosi B, Francius C, Rucchin V, et al.
Cell Mol Life Sci
. 2019 Dec;
77(20):4117-4131.
PMID: 31822965
Paralog factors are usually described as consolidating biological systems by displaying redundant functionality in the same cells. Here, we report that paralogs can also cooperate in distinct cell populations at...
7.
Bannister A, Bromma K, Sung W, Monica M, Cicon L, Howard P, et al.
Br J Radiol
. 2019 Nov;
93(1106):20190742.
PMID: 31778316
Objective: One of the major issues in current radiotherapy (RT) is the normal tissue toxicity. A smart combination of agents within the tumor would allow lowering the RT dose required...
8.
OSullivan C, Nickerson P, Krupke O, Christie J, Chen L, Mesa-Peres M, et al.
Biochem Cell Biol
. 2019 Jan;
98(1):50-60.
PMID: 30673303
During a developmental period that extends postnatally in the mouse, proliferating multipotent retinal progenitor cells produce one of 7 major cell types (rod, cone, bipolar, horizontal, amacrine, ganglion, and Müller...
9.
Litke A, Samuelson S, Delaney K, Sauve Y, Chow R
Invest Ophthalmol Vis Sci
. 2018 Dec;
59(15):5824-5835.
PMID: 30535423
Purpose: Despite numerous studies associating Visual System Homeobox 1 (VSX1), with posterior polymorphous corneal dystrophy and keratoconus, its role in these diseases is unclear. Here we examine the pathogenicity of...
10.
Ryan B, Lowe K, Hanson L, Gil T, Braun L, Howard P, et al.
BMC Genomics
. 2018 Nov;
19(1):820.
PMID: 30442116
Background: PAX6 is a homeodomain transcription factor that acts in a highly dosage-sensitive manner to regulate the development and function of the eyes, nose, central nervous system, gut, and endocrine...