Robert J Ono
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Explore the profile of Robert J Ono including associated specialties, affiliations and a list of published articles.
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22
Citations
219
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Recent Articles
1.
Park N, Fevre M, Voo Z, Ono R, Yang Y, Hedrick J
ACS Macro Lett
. 2022 May;
5(11):1247-1252.
PMID: 35614734
Postpolymerization modification is a critical strategy for the development of functional polycarbonate scaffolds for medicinal applications. To expand the scope of available postpolymerization functionalization methods, polycarbonates containing pendant thioether groups...
2.
Ono R, Lee A, Chin W, Goh W, Lee A, Yang Y, et al.
ACS Macro Lett
. 2022 May;
4(9):886-891.
PMID: 35596452
Biodegradable polycarbonate-based ABA triblock copolyelectrolytes were synthesized and formulated into physically cross-linked hydrogels. These biocompatible, cationically, and anionically charged hydrogel materials exhibited pronounced shear-thinning behavior, making them useful for a...
3.
Liu S, Ono R, Yang C, Gao S, Tan J, Hedrick J, et al.
ACS Appl Mater Interfaces
. 2018 May;
10(23):19355-19364.
PMID: 29757607
To exploit tumor and intracellular microenvironments, pH-responsive diblock copolymers of poly(ethylene glycol) and catechol-functionalized polycarbonate with acid-labile acetal bond as the linker are synthesized to prepare micellar nanoparticles that shed...
4.
Lee A, Voo Z, Chin W, Ono R, Yang C, Gao S, et al.
ACS Appl Mater Interfaces
. 2018 Mar;
10(16):13274-13282.
PMID: 29595244
In this study, bortezomib (BTZ, a cytotoxic water-insoluble anticancer drug) was encapsulated in micellar nanoparticles having a catechol-functionalized polycarbonate core through a pH-sensitive covalent bond between phenylboronic acid (PBA) in...
5.
Ono R, Lee A, Voo Z, Venkataraman S, Koh B, Yang Y, et al.
Biomacromolecules
. 2017 Jul;
18(8):2277-2285.
PMID: 28682629
Biodegradable polycarbonate-based ABA triblock copolymers were synthesized via organocatalyzed ring-opening polymerization and successfully formulated into chemically cross-linked hydrogels by strain-promoted alkyne-azide cycloaddition (SPAAC). The synthesis and cross-linking of these polymers...
6.
Liu S, Ono R, Wu H, Teo J, Liang Z, Xu K, et al.
Biomaterials
. 2017 Mar;
127:36-48.
PMID: 28279920
Effective antimicrobial agents are important arsenals in our perennial fight against communicable diseases, hospital-acquired and surgical site multidrug-resistant infections. In this study, we devise a strategy for the development of...
7.
Isik M, Tan J, Ono R, Sanchez-Sanchez A, Mecerreyes D, Yang Y, et al.
Macromol Biosci
. 2016 Jun;
16(9):1360-7.
PMID: 27273254
There is a growing interest in modern healthcare to develop systems able to fight antibiotic resistant bacteria. Antimicrobial cationic biodegradable polymers able to mimic antimicrobial peptides have shown to be...
8.
Hu Z, Willard A, Ono R, Bielawski C, Rossky P, Vanden Bout D
Nat Commun
. 2015 Sep;
6:8246.
PMID: 26391514
Conjugated polymers in the solid state usually exhibit low fluorescence quantum yields, which limit their applications in many areas such as light-emitting diodes. Despite considerable research efforts, the underlying mechanism...
9.
Reeja-Jayan B, Koen K, Ono R, Vanden Bout D, Bielawski C, Manthiram A
Phys Chem Chem Phys
. 2015 Mar;
17(16):10640-7.
PMID: 25804286
Carboxylated oligothiophenes were evaluated as interfacial modifiers between the organic poly(3-hexylthiophene) (P3HT) and inorganic TiO2 layers in bilayer hybrid polymer solar cells. Carboxylated oligothiophenes can be isolated using conventional purification...
10.
Ng V, Chan J, Sardon H, Ono R, Garcia J, Yang Y, et al.
Adv Drug Deliv Rev
. 2014 Dec;
78:46-62.
PMID: 25450263
The rapid emergence of antibiotic resistance in pathogenic microbes is becoming an imminent global public health problem. Treatment with conventional antibiotics often leads to resistance development as the majority of...