Robert J Majeska
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Explore the profile of Robert J Majeska including associated specialties, affiliations and a list of published articles.
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39
Citations
1661
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Recent Articles
1.
Coffman A, Basta-Pljakic J, Guerra R, Ebetino F, Lundy M, Majeska R, et al.
JBMR Plus
. 2021 Jul;
5(7):e10492.
PMID: 34258501
No abstract available.
2.
Lewis K, Cabahug-Zuckerman P, Boorman-Padgett J, Basta-Pljakic J, Louie J, Stephen S, et al.
Bone
. 2021 Jun;
152:116072.
PMID: 34171514
Microstructural adaptation of bone in response to mechanical stimuli is diminished with estrogen deprivation. Here we tested in vivo whether ovariectomy (OVX) alters the acute response of osteocytes, the principal...
3.
Coffman A, Basta-Pljakic J, Guerra R, Ebetino F, Lundy M, Majeska R, et al.
JBMR Plus
. 2021 Apr;
5(4):e10476.
PMID: 33869992
Bisphosphonates (BPs) are a mainstay of osteoporosis treatment; however, concerns about bone health based on oversuppression of remodeling remain. Long-term bone remodeling suppression adversely affects bone material properties with microdamage...
4.
McCutcheon S, Majeska R, Spray D, Schaffler M, Vazquez M
J Bone Miner Res
. 2020 Jan;
35(5):966-977.
PMID: 31910292
Localized apoptosis of osteocytes, the tissue-resident cells within bone, occurs with fatigue microdamage and activates bone resorption. Osteoclasts appear to target and remove dying osteocytes, resorbing damaged bone matrix as...
5.
Liu L, He Z, Xu L, Lu L, Feng H, Leong D, et al.
Ann N Y Acad Sci
. 2019 Mar;
1442(1):153-164.
PMID: 30891782
Adipokines secreted from the infrapatellar fat pad (IPFP), such as adipsin and adiponectin, have been implicated in osteoarthritis pathogenesis. CITED2, a mechanosensitive transcriptional regulator with chondroprotective activity, may modulate their...
6.
He Z, Leong D, Xu L, Hardin J, Majeska R, Schaffler M, et al.
Ann N Y Acad Sci
. 2019 Mar;
1442(1):128-137.
PMID: 30891766
Osteoarthritis (OA) pathogenesis is mediated largely through the actions of proteolytic enzymes such as matrix metalloproteinase (MMP) 13. The transcriptional regulator CITED2, which suppresses the expression of MMP13 in chondrocytes,...
7.
Leong D, Choudhury M, Hanstein R, Hirsh D, Kim S, Majeska R, et al.
Arthritis Res Ther
. 2019 Jan;
21(1):1.
PMID: 30606217
Following publication of the original article [1], the authors reported an error in Figs. 2C and 5C.
8.
Li Y, Ramcharan M, Zhou Z, Leong D, Akinbiyi T, Majeska R, et al.
Sci Rep
. 2018 Nov;
8(1):16377.
PMID: 30401955
This paper has been retracted.
9.
Cabahug-Zuckerman P, Stout Jr R, Majeska R, Thi M, Spray D, Weinbaum S, et al.
J Orthop Res
. 2017 Nov;
36(2):642-652.
PMID: 29087614
Osteocyte processes are an order of magnitude more sensitive to mechanical loading than their cell bodies. The mechanisms underlying this remarkable mechanosensitivity are not clear, but may be related to...
10.
Lewis K, Frikha-Benayed D, Louie J, Stephen S, Spray D, Thi M, et al.
Proc Natl Acad Sci U S A
. 2017 Oct;
114(44):11775-11780.
PMID: 29078317
Osteocytes are considered to be the major mechanosensory cells of bone, but how osteocytes in vivo process, perceive, and respond to mechanical loading remains poorly understood. Intracellular calcium (Ca) signaling...