Daniel J Leong
Overview
Explore the profile of Daniel J Leong including associated specialties, affiliations and a list of published articles.
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29
Citations
793
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Recent Articles
1.
Ilaltdinov A, Gong Y, Leong D, Gruson K, Zheng D, Fung D, et al.
Ann N Y Acad Sci
. 2020 Jun;
1490(1):3-12.
PMID: 32501571
Tendinopathy is a common musculoskeletal disorder characterized by chronic low-grade inflammation and tissue degeneration. Tendons have poor innate healing ability and there is currently no cure for tendinopathy. Studies elucidating...
2.
Liu L, He Z, Xu L, Lu L, Feng H, Leong D, et al.
Ann N Y Acad Sci
. 2019 Mar;
1442(1):153-164.
PMID: 30891782
Adipokines secreted from the infrapatellar fat pad (IPFP), such as adipsin and adiponectin, have been implicated in osteoarthritis pathogenesis. CITED2, a mechanosensitive transcriptional regulator with chondroprotective activity, may modulate their...
3.
He Z, Leong D, Xu L, Hardin J, Majeska R, Schaffler M, et al.
Ann N Y Acad Sci
. 2019 Mar;
1442(1):128-137.
PMID: 30891766
Osteoarthritis (OA) pathogenesis is mediated largely through the actions of proteolytic enzymes such as matrix metalloproteinase (MMP) 13. The transcriptional regulator CITED2, which suppresses the expression of MMP13 in chondrocytes,...
4.
Leong D, Choudhury M, Hanstein R, Hirsh D, Kim S, Majeska R, et al.
Arthritis Res Ther
. 2019 Jan;
21(1):1.
PMID: 30606217
Following publication of the original article [1], the authors reported an error in Figs. 2C and 5C.
5.
Li Y, Ramcharan M, Zhou Z, Leong D, Akinbiyi T, Majeska R, et al.
Sci Rep
. 2018 Nov;
8(1):16377.
PMID: 30401955
This paper has been retracted.
6.
Liu L, Hindieh J, Leong D, Sun H
J Orthop Translat
. 2018 Apr;
9:69-75.
PMID: 29662801
Tendon injuries are significant clinical problems. Current treatments often result in incomplete repair or healing, which may lead to reduced function and rupture. Stem cell-based therapy is a promising intervention...
7.
Wang A, Leong D, Cardoso L, Sun H
Pharmacol Ther
. 2018 Feb;
187:167-179.
PMID: 29481810
Arthritis is a chronic disease of joints. It is highly prevalent, particularly in the elderly, and is commonly associated with pain that interferes with quality of life. Because of its...
8.
Cobelli N, Leong D, Sun H
Ann N Y Acad Sci
. 2017 Nov;
1410(1):57-67.
PMID: 29125180
Exosomes are nanovesicles secreted from cells that play key roles in intercellular communication. They carry unique content derived from parental cells and are capable of transferring this cargo between cells....
9.
Wang A, Leong D, He Z, Xu L, Liu L, Kim S, et al.
Int J Mol Sci
. 2016 Dec;
17(12).
PMID: 27941690
Procyanidins are a family of plant metabolites that have been suggested to mitigate osteoarthritis pathogenesis in mice. However, the underlying mechanism is largely unknown. This study aimed to determine whether...
10.
Leong D, Sun H
Ann N Y Acad Sci
. 2016 Oct;
1383(1):88-96.
PMID: 27706825
Tendon injuries are common and present a clinical challenge because they often respond poorly to treatment and require prolonged rehabilitation. Current treatments often do not completely repair or regenerate the...