Robert J Garriock
Overview
Explore the profile of Robert J Garriock including associated specialties, affiliations and a list of published articles.
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21
Citations
544
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Recent Articles
1.
Garriock R, Chalamalasetty R, Zhu J, Kennedy M, Kumar A, Mackem S, et al.
Development
. 2020 Mar;
147(8).
PMID: 32156757
Despite the importance of Wnt signaling for adult intestinal stem cell homeostasis and colorectal cancer, relatively little is known about its role in colon formation during embryogenesis. The development of...
2.
Chalamalasetty R, Ajima R, Garriock R, Kennedy M, Tessarollo L, Yamaguchi T
Genesis
. 2016 Jul;
54(9):497-502.
PMID: 27411055
Wnt/β-catenin signals are important regulators of embryonic and adult stem cell self-renewal and differentiation and play causative roles in tumorigenesis. Purified recombinant Wnt3a protein, or Wnt3a-conditioned culture medium, has been...
3.
Kumar A, Chalamalasetty R, Kennedy M, Thomas S, Inala S, Garriock R, et al.
Mol Cell Biol
. 2016 Apr;
36(12):1793-802.
PMID: 27090637
The Wnt/β-catenin signaling pathway controls embryonic development and adult stem cell maintenance through the regulation of transcription. Failure to downregulate Wnt signaling can result in embryonic malformations and cancer, highlighting...
4.
Kennedy M, Chalamalasetty R, Thomas S, Garriock R, Jailwala P, Yamaguchi T
Proc Natl Acad Sci U S A
. 2016 Mar;
113(13):3545-50.
PMID: 26969725
The ancient, highly conserved, Wnt signaling pathway regulates cell fate in all metazoans. We have previously shown that combined null mutations of the specificity protein (Sp) 1/Klf-like zinc-finger transcription factors...
5.
Garriock R, Chalamalasetty R, Kennedy M, Canizales L, Lewandoski M, Yamaguchi T
Development
. 2015 Apr;
142(9):1628-38.
PMID: 25922526
In the development of the vertebrate body plan, Wnt3a is thought to promote the formation of paraxial mesodermal progenitors (PMPs) of the trunk region while suppressing neural specification. Recent lineage-tracing...
6.
Chalamalasetty R, Garriock R, Dunty Jr W, Kennedy M, Jailwala P, Si H, et al.
Development
. 2014 Nov;
141(22):4285-97.
PMID: 25371364
Neuromesodermal (NM) stem cells generate neural and paraxial presomitic mesoderm (PSM) cells, which are the respective progenitors of the spinal cord and musculoskeleton of the trunk and tail. The Wnt-regulated...
7.
Bressan M, Yang P, Louie J, Navetta A, Garriock R, Mikawa T
Development
. 2014 Oct;
141(21):4149-57.
PMID: 25273084
Efficient blood flow depends on two developmental processes that occur within the atrioventricular junction (AVJ) of the heart: conduction delay, which entrains sequential chamber contraction; and valve formation, which prevents...
8.
Garriock R, Mikawa T, Yamaguchi T
Methods
. 2013 Jul;
66(3):365-9.
PMID: 23816793
The proepicardium (PE) is an embryonic tissue that gives rise to multipotent vascular progenitors. Most notably the PE gives rise to the epicardium, cardiac fibroblasts, myocardium, and coronary vessels including...
9.
Warkman A, Whitman S, Miller M, Garriock R, Schwach C, Gregorio C, et al.
Cytoskeleton (Hoboken)
. 2012 Mar;
69(5):324-35.
PMID: 22422726
The mammalian heart expresses two myosin heavy chain (MYH) genes (Myh6 and Myh7), which are major components of the thick filaments of the sarcomere. We have determined that a third...
10.
Garriock R, Mikawa T
Semin Cell Dev Biol
. 2011 Oct;
22(9):985-92.
PMID: 22020129
Of the many models to study vascular biology the avian embryo remains an informative and powerful model system that has provided important insights into endothelial cell recruitment, assembly and remodeling...