Robert J Gaivin
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Explore the profile of Robert J Gaivin including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
173
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Recent Articles
1.
Khan S, Gaivin R, Liu Z, Li V, Samuels I, Son J, et al.
bioRxiv
. 2025 Feb;
PMID: 39975070
Graphical Abstract:
2.
Kumar M, Gaivin R, Khan S, Fedorov Y, Adams D, Zhao W, et al.
Int J Biol Macromol
. 2023 Jun;
244:125328.
PMID: 37307967
Diabetes is a major public health problem due to morbidity and mortality associated with end organ complications. Uptake of fatty acids by Fatty Acid Transport Protein-2 (FATP2) contributes to hyperglycemia,...
3.
Lessieur E, Fogerty J, Gaivin R, Song P, Perkins B
Invest Ophthalmol Vis Sci
. 2017 Jan;
58(1):448-460.
PMID: 28118669
Purpose: Joubert syndrome (JBTS) is an autosomal recessive ciliopathy with considerable phenotypic variability. In addition to central nervous system abnormalities, a subset of JBTS patients exhibit retinal dystrophy and/or kidney...
4.
Daniele L, Emran F, Lobo G, Gaivin R, Perkins B
Invest Ophthalmol Vis Sci
. 2016 Jun;
57(7):2942-54.
PMID: 27273592
Purpose: Tail-anchored (TA) proteins contain a single hydrophobic domain at the C-terminus and are posttranslationally inserted into the ER membrane via the GET (guided entry of tail-anchored proteins) pathway. The...
5.
Fan C, Gaivin R, Marth T, Willard B, Levine M, Lietman S
Biochem Biophys Res Commun
. 2012 Jul;
425(1):25-32.
PMID: 22820184
SH3BP2 activating mutations lead to an unique clinical condition in which patients develop symmetrical bone resorptive lesions of the jaw, a condition termed cherubism. Due to this specific temporal sequence...
6.
Kawamoto T, Fan C, Gaivin R, Levine M, Lietman S
J Orthop Res
. 2011 Mar;
29(10):1521-7.
PMID: 21448930
Germline mutations in SH3BP2 gene have been identified in patients with cherubism, a skeletal disorder characterized by excessive osteoclastic bone resorption that is limited to the mandible and maxilla. We...
7.
Gupta M, Papay R, Jurgens C, Gaivin R, Shi T, Doze V, et al.
Mol Pharmacol
. 2009 Jun;
76(2):314-26.
PMID: 19487244
The understanding of the function of alpha(1)-adrenergic receptors in the brain has been limited due to a lack of specific ligands and antibodies. We circumvented this problem by using transgenic...
8.
Shi T, Gaivin R, McCune D, Gupta M, Perez D
J Recept Signal Transduct Res
. 2007 Mar;
27(1):27-45.
PMID: 17365508
The function and distribution of alpha1-adrenergic receptor (AR) subtypes in prostate cancer cells is well characterized. Previous studies have used RNA localization or low-avidity antibodies in tissue or cell lines...
9.
Chen L, Hodges R, Funaki C, Zoukhri D, Gaivin R, Perez D, et al.
Am J Physiol Cell Physiol
. 2006 Jun;
291(5):C946-56.
PMID: 16760267
Transactivation of EGF receptors by G protein-coupled receptors is a well-known phenomenon. This process involves the ectodomain shedding of growth factors in the EGF family by matrix metalloproteinases. However, many...
10.
Shi T, Duan Z, Papay R, Pluskota E, Gaivin R, de la Motte C, et al.
Mol Pharmacol
. 2006 Apr;
70(1):129-42.
PMID: 16617165
alpha1-Adrenergic receptor (alpha1-ARs) subtypes (alpha1A, alpha1B, and alpha1D) regulate multiple signal pathways, such as phospholipase C, protein kinase C (PKC), and mitogen-activated protein kinases. We employed oligonucleotide microarray technology to...