Robert J Ely
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Explore the profile of Robert J Ely including associated specialties, affiliations and a list of published articles.
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5
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53
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Recent Articles
1.
Ely R, Yu Z, Morken J
Tetrahedron Lett
. 2015 Jun;
56(23):3402-3405.
PMID: 26028782
The Ni-catalyzed hydroboration of dienols occurs in a 1,4 fashion and delivers a syn-propionate motif in high diastereoselectivity and with a stereodefined trisubstituted crotylboronic ester. The boronic ester can be...
2.
Yu Z, Ely R, Morken J
Angew Chem Int Ed Engl
. 2014 Jul;
53(36):9632-6.
PMID: 25045037
The marine natural product (+)-discodermolide was first isolated in 1990 and, to this day, remains a compelling synthesis target. Not only does the compound possess fascinating biological activity, but it...
3.
Ren L, Wenglowsky S, Miknis G, Rast B, Buckmelter A, Ely R, et al.
Bioorg Med Chem Lett
. 2011 Jan;
21(4):1243-7.
PMID: 21251822
The development of inhibitors of B-Raf(V600E) serine-threonine kinase is described. Various head-groups were examined to optimize inhibitor activity and ADME properties. Several of the head-groups explored, including naphthol, phenol and...
4.
Ely R, Morken J
Org Lett
. 2010 Sep;
12(19):4348-51.
PMID: 20828186
A catalytic stereoselective 1,4-diboration of conjugated dienes with B(2)(pin)(2) was accomplished with Ni(cod)(2) and PCy(3) as the catalyst. This reaction broadens the substrate scope of current methods for catalytic diene...
5.
Ely R, Morken J
J Am Chem Soc
. 2010 Feb;
132(8):2534-5.
PMID: 20136142
A catalytic regio- and stereoselective 1,4-hydroboration of 1,3-dienes was accomplished with pinacolborane in the presence of Ni(cod)(2) and PCy(3). This reaction exhibits broad substrate scope operating on a range of...