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Robert Ishmukhametov

Explore the profile of Robert Ishmukhametov including associated specialties, affiliations and a list of published articles. Areas
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Articles 14
Citations 340
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Recent Articles
1.
Sobti M, Zeng Y, Walshe J, Brown S, Ishmukhametov R, Stewart A
Commun Biol . 2023 Jan; 6(1):26. PMID: 36631659
FF ATP synthase functions as a biological generator and makes a major contribution to cellular energy production. Proton flow generates rotation in the F motor that is transferred to the...
2.
Kinosita Y, Mikami N, Li Z, Braun F, Quax T, van der Does C, et al.
Proc Natl Acad Sci U S A . 2020 Oct; 117(43):26766-26772. PMID: 33051299
Archaea swim using the archaellum (archaeal flagellum), a reversible rotary motor consisting of a torque-generating motor and a helical filament, which acts as a propeller. Unlike the bacterial flagellar motor...
3.
Sobti M, Walshe J, Wu D, Ishmukhametov R, Zeng Y, Robinson C, et al.
Nat Commun . 2020 May; 11(1):2615. PMID: 32457314
FF ATP synthase functions as a biological rotary generator that makes a major contribution to cellular energy production. It comprises two molecular motors coupled together by a central and a...
4.
Sobti M, Ishmukhametov R, Stewart A
Methods Mol Biol . 2019 Oct; 2073:73-84. PMID: 31612437
ATP synthase is an essential enzyme found in all known forms of life, generating the majority of cellular energy via a rotary catalytic mechanism. Here, we describe the in-depth methods...
5.
Sobti M, Ishmukhametov R, Bouwer J, Ayer A, Suarna C, Smith N, et al.
Elife . 2019 Mar; 8. PMID: 30912741
ATP synthase produces the majority of cellular energy in most cells. We have previously reported cryo-EM maps of autoinhibited ATP synthase imaged without addition of nucleotide (Sobti et al. 2016),...
6.
Martin J, Ishmukhametov R, Spetzler D, Hornung T, Frasch W
Proc Natl Acad Sci U S A . 2018 May; 115(22):5750-5755. PMID: 29760063
The angular velocity profile of the 120° F-ATPase power stroke was resolved as a function of temperature from 16.3 to 44.6 °C using a Δμ = -31.25 at a time...
7.
Sobti M, Smits C, Wong A, Ishmukhametov R, Stock D, Sandin S, et al.
Elife . 2016 Dec; 5. PMID: 28001127
A molecular model that provides a framework for interpreting the wealth of functional information obtained on the F-ATP synthase has been generated using cryo-electron microscopy. Three different states that relate...
8.
Martin J, Ishmukhametov R, Hornung T, Ahmad Z, Frasch W
Proc Natl Acad Sci U S A . 2014 Feb; 111(10):3715-20. PMID: 24567403
F1-ATPase, the catalytic complex of the ATP synthase, is a molecular motor that can consume ATP to drive rotation of the γ-subunit inside the ring of three αβ-subunit heterodimers in...
9.
Hornung T, Martin J, Spetzler D, Ishmukhametov R, Frasch W
Methods Mol Biol . 2011 Aug; 778:273-89. PMID: 21809213
Single-molecule measurements of rotation catalyzed by the F(1)-ATPase or the F(o)F(1) ATP synthase have provided new insights into the molecular mechanisms of the F(1) and F(o) molecular motors. We recently...
10.
Ishmukhametov R, Hornung T, Spetzler D, Frasch W
EMBO J . 2010 Nov; 29(23):3911-23. PMID: 21037553
Although single-molecule experiments have provided mechanistic insight for several molecular motors, these approaches have proved difficult for membrane bound molecular motors like the F₀F₁-ATP synthase, in which proton transport across...