Robert Franzen
Overview
Explore the profile of Robert Franzen including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
28
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0
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Recent Articles
1.
Tienaho J, Karonen M, Muilu-Makela R, Kaseva J, de Pedro N, Vicente F, et al.
Planta Med
. 2020 Jun;
86(13-14):1009-1024.
PMID: 32521558
Despite the continuing interest in various plant and natural products, only a small portion of the biologically active compounds from nature has been discovered and exploited. In this study, antioxidant...
2.
Tienaho J, Karonen M, Muilu-Makela R, Wahala K, Denegri E, Franzen R, et al.
Molecules
. 2019 Nov;
24(22).
PMID: 31698823
The authors wish to make the following corrections to this paper published in [...].
3.
Tienaho J, Karonen M, Muilu-Makela R, Wahala K, Denegri E, Franzen R, et al.
Molecules
. 2019 Jun;
24(12).
PMID: 31242564
Endophytes are microorganisms living inside plant hosts and are known to be beneficial for the host plant vitality. In this study, we isolated three endophytic fungus species from the roots...
4.
Synthesis and biological screening for cytotoxic activity of N-substituted indolines and morpholines
Doan P, Karjalainen A, Chandraseelan J, Sandberg O, Yli-Harja O, Rosholm T, et al.
Eur J Med Chem
. 2016 May;
120:296-303.
PMID: 27214140
Development of novel anticancer drugs is inevitable to improve treatment of cancers. In this study, novel derivatives of indoline and morpholine were synthesized and tested for their cytotoxic effects on...
5.
Tienaho J, Sarjala T, Franzen R, Karp M
J Microbiol Methods
. 2015 Sep;
118:78-80.
PMID: 26327540
A new method is described for the rapid real-time screening of antioxidative properties using a recombinant Escherichia coli DPD2511 biosensor. This microplate technique, without time-consuming pre-incubations and handling, has potential...
6.
Rosholm T, Gois P, Franzen R, Candeias N
ChemistryOpen
. 2015 Apr;
4(1):39-46.
PMID: 25861569
The multicomponent Petasis borono-Mannich (PBM) reaction is a useful tool for the preparation of complex molecules in a single step from boronic acids, aldehydes/ketones, and amines. Here, we describe the...
7.
Nemoto T, Yamamoto E, Franzen R, Fukuyama T, Wu R, Fukamachi T, et al.
Org Lett
. 2010 Jan;
12(4):872-5.
PMID: 20092264
The first enantioselective total synthesis of tangutorine has been achieved, wherein a Pd-catalyzed asymmetric allylic amination using a chiral diaminophosphine oxide (DIAPHOX) preligand was the key step.
8.
Ward W, Swartz C, Hanley N, Whitaker J, Franzen R, DeMarini D
Environ Mol Mutagen
. 2009 Jul;
51(1):69-79.
PMID: 19598237
The relationship between chemical structure and biological activity has been examined for various compounds and endpoints for decades. To explore this question relative to global gene expression, we performed microarray...
9.
Franzen R, Tois J
Comb Chem High Throughput Screen
. 2003 Jul;
6(5):433-44.
PMID: 12871050
The Nobel Prize in Chemistry 1902 was given to Hermann Emil Fischer "in recognition of the extraordinary services he had rendered by his work on sugar and purine synthesis". This...