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Robert E Campbell

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Articles 139
Citations 9074
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Recent Articles
1.
Bareghamyan A, Deng C, Daoudi S, Yadav S, Lu X, Zhang W, et al.
bioRxiv . 2025 Feb; PMID: 39974889
Recombinant optogenetic and chemogenetic proteins are potent tools for manipulating neuronal activity and controlling neural circuit function. However, there are few analogous tools for manipulating the structure of neural circuits....
2.
Tyurikova O, Kopach O, Zheng K, Rathore D, Codadu N, Wu S, et al.
Cell Rep . 2025 Feb; 44(2):115299. PMID: 39951378
Intense brain activity elevates extracellular potassium, potentially leading to overexcitation and seizures. Astrocytes are crucial for restoring healthy potassium levels, and an emerging focus on their Kir4.1 channels has reopened...
3.
Shaykevich S, Little J, Qian Y, Paquet M, Campbell R, Razansky D, et al.
Photoacoustics . 2025 Jan; 41():100671. PMID: 39811063
Measuring whole-brain distributed functional activity is an important unmet need in neuroscience, requiring high temporal resolution and cellular specificity across large volumes. Functional optoacoustic neuro-tomography (FONT) with genetically encoded calcium...
4.
Fink R, Imai S, Gockel N, Lauer G, Renken K, Wietek J, et al.
bioRxiv . 2025 Jan; PMID: 39763884
Genetically encoded calcium (Ca) indicators (GECIs) are widely used for imaging neuronal activity, yet current limitations of existing red fluorescent GECIs have constrained their applicability. The inherently dim fluorescence and...
5.
Takeuchi S, Imai S, Terai T, Campbell R
RSC Chem Biol . 2024 Dec; 6(2):170-174. PMID: 39678364
A chemigenetic indicator with an affinity suitable for imaging of intracellular sodium ions (Na) in mammalian cells was developed. The indicator, based on a chimera of green fluorescent protein (GFP)...
6.
Cheng D, Ouyang Z, He X, Nasu Y, Wen Y, Terai T, et al.
J Am Chem Soc . 2024 Nov; 146(51):35117-35128. PMID: 39601449
Potassium ion (K) is the most abundant metal ion in cells and plays an indispensable role in practically all biological systems. Although there have been reports of both synthetic and...
7.
Tamagawa K, Campbell R, Terai T
Chembiochem . 2024 Nov; 25(24):e202400617. PMID: 39512024
Cells utilize ubiquitin as a posttranslational protein modifier to convey various signals such as proteasomal degradation. The dysfunction of ubiquitylation or following proteasomal degradation can give rise to the accumulation...
8.
Tsao K, Imai S, Chang M, Hario S, Terai T, Campbell R
Cell Chem Biol . 2024 Sep; 31(9):1652-1664. PMID: 39236713
Synthetic-based fluorescent chemosensors and protein-based fluorescent biosensors are two well-established classes of tools for visualizing and monitoring biological processes in living tissues. Chemigenetic sensors, created using a combination of both...
9.
Fernandez-Moncada I, Lavanco G, Fundazuri U, Bollmohr N, Mountadem S, Dalla Tor T, et al.
Nat Commun . 2024 Aug; 15(1):6842. PMID: 39122700
Astrocytes control brain activity via both metabolic processes and gliotransmission, but the physiological links between these functions are scantly known. Here we show that endogenous activation of astrocyte type-1 cannabinoid...
10.
Hochgeschwender U, Campbell R, Mizuno H
Neurophotonics . 2024 Jul; 11(2):024200. PMID: 38948889
The editorial introduces the Special Section on Molecular Neurophotonics.