Robert C Thompson
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Explore the profile of Robert C Thompson including associated specialties, affiliations and a list of published articles.
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63
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4582
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Recent Articles
11.
Carter B, Hamilton D, Thompson R
J Undergrad Neurosci Educ
. 2018 Jan;
16(1):A83-A88.
PMID: 29371846
Knowledge and application of experimental design principles are essential components of scientific methodology, and experience with these skills is fundamental for participating in scientific research. However, undergraduates often enter the...
12.
Baker M, Lindell S, Driscoll C, Zhou Z, Yuan Q, Schwandt M, et al.
Proc Natl Acad Sci U S A
. 2017 Oct;
114(44):11769-11774.
PMID: 29078292
Adaptations to stress can occur through epigenetic processes and may be a conduit for informing offspring of environmental challenge. We employed ChIP-sequencing for H3K4me3 to examine effects of early maternal...
13.
Azevedo J, Carter B, Meng F, Turner D, Dai M, Schatzberg A, et al.
J Psychiatr Res
. 2016 Jul;
82:58-67.
PMID: 27468165
MicroRNAs (miRNAs) are small, non-coding RNAs acting as post-transcriptional regulators of gene expression. Though implicated in multiple CNS disorders, miRNAs have not been examined in any psychiatric disease state in...
14.
Flagel S, Chaudhury S, Waselus M, Kelly R, Sewani S, Clinton S, et al.
Proc Natl Acad Sci U S A
. 2016 Apr;
113(20):E2861-70.
PMID: 27114539
This study provides a demonstration in the rat of a clear genetic difference in the propensity for addiction-related behaviors following prolonged cocaine self-administration. It relies on the use of selectively...
15.
Singer B, Newstead M, Zeng X, Cooke C, Thompson R, Singer K, et al.
PLoS One
. 2016 Feb;
11(2):e0149136.
PMID: 26862765
Survivors of sepsis often experience long-term cognitive and functional decline. Previous studies utilizing lipopolysaccharide injection and cecal ligation and puncture in rodent models of sepsis have demonstrated changes in depressive-like...
16.
Medina A, Watson S, Bunney Jr W, Myers R, Schatzberg A, Barchas J, et al.
J Psychiatr Res
. 2015 Nov;
72:15-21.
PMID: 26519765
Background: Glial cells are essential in maintaining synaptic function. In glutamatergic synapses astrocytes remove the products of neural activity, (i.e. potassium, glutamate and excess water) from the synaptic cleft and...
17.
Wang X, Huang T, Zhao Y, Zheng Q, Thompson R, Bu G, et al.
Cell Rep
. 2014 Dec;
9(3):1023-33.
PMID: 25437557
Patients with Down syndrome (DS) invariably develop Alzheimer's disease (AD) pathology in their 40s. We have recently found that overexpression of a chromosome 21-encoded microRNA-155 results in decreased levels of...
18.
Huang H, Redmond T, Kubish G, Gupta S, Thompson R, Turner D, et al.
J Mol Neurosci
. 2014 Sep;
55(3):684-705.
PMID: 25189318
As members of the proneural basic-helix-loop-helix (bHLH) family of transcription factors, Ascl1 and Neurog2 direct the differentiation of specific populations of neurons at various times and locations within the developing...
19.
Turner C, Thompson R, Bunney W, Schatzberg A, Barchas J, Myers R, et al.
Front Hum Neurosci
. 2014 May;
8:238.
PMID: 24795602
Given the emergent interest in biomarkers for mood disorders, we assessed gene expression in the choroid plexus (CP), the region that produces cerebrospinal fluid (CSF), in individuals with major depressive...
20.
Hamilton D, Cooke C, Carter B, Akil H, Watson S, Thompson R
Physiol Genomics
. 2014 Feb;
46(8):290-301.
PMID: 24569673
Mental health disorders involving altered reward, emotionality, and anxiety are thought to result from the interaction of individual predisposition (genetic factors) and personal experience (environmental factors), although the mechanisms that...