Robert C Smart
Overview
Explore the profile of Robert C Smart including associated specialties, affiliations and a list of published articles.
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Articles
26
Citations
876
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0
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Recent Articles
1.
Sohn A, Witherspoon J, Smart R, Muddiman D
Anal Bioanal Chem
. 2025 Feb;
417(8):1649-1661.
PMID: 39900867
Leveraging a depth profiling approach expands the chemical elucidation of mass spectrometry imaging techniques to another dimension. Three-dimensional MSI (3D MSI) reveals the distribution of analytes with greater anatomical detail...
2.
Witherspoon J, Hall J, Jima D, Atkins H, Wamsley N, Major M, et al.
Redox Biol
. 2024 Jul;
75:103261.
PMID: 38963974
Squamous cell carcinomas (SCCs), including lung, head & neck, bladder, and skin SCCs often display constitutive activation of the KEAP1-NRF2 pathway. Constitutive activation is achieved through multiple mechanisms, including activating...
3.
Kotlarz N, McCord J, Collier D, Suzanne Lea C, Strynar M, Lindstrom A, et al.
Environ Health Perspect
. 2024 Feb;
132(2):29002.
PMID: 38358997
No abstract available.
4.
House J, Gray S, Owen J, Jima D, Smart R, Hall J
Innate Immun
. 2023 Apr;
29(1-2):14-24.
PMID: 37094088
The skin is the first line of defense to cutaneous microbes and viruses, and epidermal keratinocytes play a critical role in preventing infection by viruses and pathogens through activation of...
5.
Kaur P, Barnes R, Pan H, Detwiler A, Liu M, Mahn C, et al.
Nucleic Acids Res
. 2021 Dec;
49(22):13000-13018.
PMID: 34883513
The telomere specific shelterin complex, which includes TRF1, TRF2, RAP1, TIN2, TPP1 and POT1, prevents spurious recognition of telomeres as double-strand DNA breaks and regulates telomerase and DNA repair activities...
6.
Kotlarz N, McCord J, Collier D, Suzanne Lea C, Strynar M, Lindstrom A, et al.
Environ Health Perspect
. 2020 Aug;
128(8):89002.
PMID: 32812829
No abstract available.
7.
Kotlarz N, McCord J, Collier D, Suzanne Lea C, Strynar M, Lindstrom A, et al.
Environ Health Perspect
. 2020 Jul;
128(7):77005.
PMID: 32697103
Background: From 1980 to 2017, a fluorochemical manufacturing facility discharged wastewater containing poorly understood per- and polyfluoroalkyl substances (PFAS) to the Cape Fear River, the primary drinking water source for...
8.
Tam H, Hall J, Messenger Z, Jima D, House J, Linder K, et al.
Carcinogenesis
. 2019 Jan;
40(9):1099-1109.
PMID: 30698678
p53 is activated by DNA damage and oncogenic stimuli to regulate senescence, apoptosis and cell-cycle arrest, which are essential to prevent cancer. Here, we utilized UVB radiation, a potent inducer...
9.
Messenger Z, Hall J, Jima D, House J, Tam H, Tokarz D, et al.
Cell Death Dis
. 2018 Oct;
9(11):1054.
PMID: 30323292
Therapeutic targeting of specific genetic changes in cancer has proven to be an effective therapy and the concept of synthetic lethality has emerged. CCAAT/enhancer-binding protein-β (C/EBPβ), a basic leucine zipper...
10.
Hall J, Bereman M, Nepomuceno A, Thompson E, Muddiman D, Smart R
Cell Cycle
. 2014 Dec;
13(22):3602-10.
PMID: 25483090
The bZIP transcription factor, C/EBPα is highly inducible by UVB and other DNA damaging agents in keratinocytes. C/EBPα-deficient keratinocytes fail to undergo cell cycle arrest in G1 in response to...