Robert B Zurier
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Explore the profile of Robert B Zurier including associated specialties, affiliations and a list of published articles.
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27
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556
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Recent Articles
1.
Zurier R, Burstein S
FASEB J
. 2016 Jul;
30(11):3682-3689.
PMID: 27435265
Cannabinoids apparently act on inflammation through mechanisms different from those of agents such as nonsteroidal anti-inflammatory drugs (NSAIDs). As a class, the cannabinoids are generally free from the adverse effects...
2.
Tepper M, Zurier R, Burstein S
Bioorg Med Chem
. 2014 May;
22(13):3245-51.
PMID: 24856183
Ajulemic acid, a side-chain analog of Δ(8)-THC-11-oic acid, was designed as a potent therapeutic agent free of the psychotropic adverse effects typical of most cannabinoids. Subsequent studies of ajulemic acid...
3.
Reed G, Leung K, Rossetti R, Vanbuskirk S, Sharp J, Zurier R
Evid Based Complement Alternat Med
. 2014 May;
2014:857456.
PMID: 24803948
Objective. To determine whether a combination of borage seed oil rich in gamma linolenic acid (GLA) and fish oil rich in eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) is superior...
4.
Olendzki B, Leung K, Van Buskirk S, Reed G, Zurier R
Evid Based Complement Alternat Med
. 2011 Oct;
2011:827286.
PMID: 22007257
The gap in mortality between patients with rheumatoid arthritis (RA) and the general population (1.5-3.0 fold risk) is increasing. This disparity is attributable mainly to cardiovascular disease (CVD), as the...
5.
Burstein S, Zurier R
AAPS J
. 2009 Feb;
11(1):109-19.
PMID: 19199042
This review covers reports published in the last 5 years on the anti-inflammatory activities of all classes of cannabinoids, including phytocannabinoids such as tetrahydrocannabinol and cannabidiol, synthetic analogs such as...
6.
Zurier R, Sun Y, George K, Stebulis J, Rossetti R, Skulas A, et al.
FASEB J
. 2009 Jan;
23(5):1503-9.
PMID: 19124557
Ajulemic acid (AjA), a synthetic nonpsychoactive cannabinoid, and lipoxin A(4) (LXA(4)), an eicosanoid formed from sequential actions of 5- and 15-lipoxygenases (LOX), facilitate resolution of inflammation. The purpose of this...
7.
Stebulis J, Johnson D, Rossetti R, Burstein S, Zurier R
Life Sci
. 2008 Oct;
83(19-20):666-70.
PMID: 18840450
Aims: To better understand mechanisms whereby Ajulemic acid (AjA), a synthetic antiinflammatory cannabinoid, promotes resolution of acute and chronic inflammation in animal models, we investigated its influence on cyclooxygenase 2...
8.
Han G, ONeil-Andersen N, Zurier R, Lawrence D
Cell Immunol
. 2008 Jul;
253(1-2):92-101.
PMID: 18649874
Accumulating evidences support that CD4(+)CD25(high) T regulatory (Treg) cells play an essential role in controlling and preventing autoimmunity. Paradoxically, RA patients have elevated numbers of circulating CD4(+)CD25(high) T cells, however,...
9.
Parker J, Atez F, Rossetti R, Skulas A, Patel R, Zurier R
Rheumatol Int
. 2007 Nov;
28(7):631-5.
PMID: 18040689
Interleukin-6 (IL-6) is a multifunctional cytokine which contributes to inflammation and tissue injury in several diseases. Thus, inhibition of IL-6 production may be a useful strategy for treatment of patients...
10.
George K, Saltman L, Stein G, Lian J, Zurier R
J Cell Physiol
. 2007 Sep;
214(3):714-20.
PMID: 17786950
Oral administration of ajulemic acid (AjA), a cannabinoid acid devoid of psychoactivity, prevents joint tissue injury in rats with adjuvant induced arthritis. Because activation of osteoclasts is central to the...