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Robert A Edwards

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Articles 218
Citations 20585
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Recent Articles
11.
Bouras G, Houtak G, Wick R, Mallawaarachchi V, Roach M, Papudeshi B, et al.
Microb Genom . 2024 May; 10(5). PMID: 38717808
Improvements in the accuracy and availability of long-read sequencing mean that complete bacterial genomes are now routinely reconstructed using hybrid (i.e. short- and long-reads) assembly approaches. Complete genomes allow a...
12.
Hosohama L, Tifrea D, Nee K, Park S, Wu J, Habowski A, et al.
bioRxiv . 2024 May; PMID: 38712298
Several classification systems have been developed to define tumor subtypes in colorectal cancer (CRC). One system proposes that tumor heterogeneity derives in part from distinct cancer stem cell populations that...
13.
Brame J, Liddicoat C, Abbott C, Edwards R, Robinson J, Gauthier N, et al.
Ecol Evol . 2024 May; 14(5):e11239. PMID: 38694752
Butyrate-producing bacteria are found in many outdoor ecosystems and host organisms, including humans, and are vital to ecosystem functionality and human health. These bacteria ferment organic matter, producing the short-chain...
14.
Coulon P, Prakash S, Dhanushkodi N, Srivastava R, Zayou L, Tifrea D, et al.
Front Immunol . 2024 Apr; 15:1343716. PMID: 38605956
Background: Cross-reactive SARS-CoV-2-specific memory CD4 and CD8 T cells are present in up to 50% of unexposed, pre-pandemic, healthy individuals (UPPHIs). However, the characteristics of cross-reactive memory CD4 and CD8...
15.
McNair K, Salamon P, Edwards R, Segall A
BMC Bioinformatics . 2024 Feb; 25(1):82. PMID: 38389044
Background: One of the stranger phenomena that can occur during gene translation is where, as a ribosome reads along the mRNA, various cellular and molecular properties contribute to stalling the...
16.
Prakash S, Dhanushkodi N, Zayou L, Ibraim I, Quadiri A, Coulon P, et al.
Front Immunol . 2024 Feb; 15:1328905. PMID: 38318166
Background: The coronavirus disease 2019 (COVID-19) pandemic has created one of the largest global health crises in almost a century. Although the current rate of Severe acute respiratory syndrome coronavirus...
17.
Inglis L, Roach M, Edwards R
Microb Genom . 2024 Jan; 10(1). PMID: 38264887
Phages integrated into a bacterial genome - called prophages - continuously monitor the vigour of the host bacteria to determine when to escape the genome and to protect their host...
18.
Cook R, Telatin A, Bouras G, Camargo A, Larralde M, Edwards R, et al.
bioRxiv . 2024 Jan; PMID: 38187747
The majority of bacteriophage diversity remains uncharacterised, and new intriguing mechanisms of their biology are being continually described. Members of some phage lineages, such as the , repurpose stop codons...
19.
Dhanushkodi N, Prakash S, Quadiri A, Zayou L, Srivastava R, Shaik A, et al.
J Immunol . 2024 Jan; 212(4):576-585. PMID: 38180084
SARS-CoV-2 variants of concern (VOCs) continue to evolve and reemerge with chronic inflammatory long COVID sequelae, necessitating the development of anti-inflammatory therapeutic molecules. Therapeutic effects of the receptor for advanced...
20.
Bouras G, Houtak G, Wick R, Mallawaarachchi V, Roach M, Papudeshi B, et al.
bioRxiv . 2024 Jan; PMID: 38168369
Improvements in the accuracy and availability of long-read sequencing mean that complete bacterial genomes are now routinely reconstructed using hybrid (i.e. short- and long-reads) assembly approaches. Complete genomes allow a...