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George Bouras

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Citations 620
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Recent Articles
1.
Papudeshi B, Roach M, Mallawaarachchi V, Bouras G, Grigson S, Giles S, et al.
Bioinform Adv . 2025 Feb; 5(1):vbaf004. PMID: 39897948
Motivation: Phage therapy offers a viable alternative for bacterial infections amid rising antimicrobial resistance. Its success relies on selecting safe and effective phage candidates that require comprehensive genomic screening to...
2.
Papudeshi B, Roach M, Mallawaarachchi V, Bouras G, Grigson S, Giles S, et al.
bioRxiv . 2024 Nov; PMID: 39605506
Motivation: Phage therapy is a viable alternative for treating bacterial infections amidst the escalating threat of antimicrobial resistance. However, the therapeutic success of phage therapy depends on selecting safe and...
3.
Ramezanpour M, Feizi S, Arachchige H, Bouras G, Cooksley C, Shaghayegh G, et al.
Int Forum Allergy Rhinol . 2024 Nov; 15(3):267-277. PMID: 39512125
Background: Chronic rhinosinusitis (CRS) is a persistent inflammatory condition of the sinus mucosa. While Staphylococcus aureus has been shown to play a significant role in mucosal barrier disruption in CRS...
4.
Mallawaarachchi V, Wickramarachchi A, Xue H, Papudeshi B, Grigson S, Bouras G, et al.
Brief Bioinform . 2024 Jul; 25(5). PMID: 39082646
Metagenomics involves the study of genetic material obtained directly from communities of microorganisms living in natural environments. The field of metagenomics has provided valuable insights into the structure, diversity and...
5.
Cook R, Telatin A, Bouras G, Camargo A, Larralde M, Edwards R, et al.
ISME Commun . 2024 Jun; 4(1):ycae079. PMID: 38939532
The majority of bacteriophage diversity remains uncharacterized, and new intriguing mechanisms of their biology are being continually described. Members of some phage lineages, such as the , repurpose stop codons...
6.
Bouras G, Judd L, Edwards R, Vreugde S, Stinear T, Wick R
Microb Genom . 2024 Jun; 10(6). PMID: 38833287
It is now possible to assemble near-perfect bacterial genomes using Oxford Nanopore Technologies (ONT) long reads, but short-read polishing is usually required for perfection. However, the effect of short-read depth...
7.
Candy N, Zhang A, Bouras G, Jukes A, Santoreneos S, Vrodos N, et al.
Oper Neurosurg (Hagerstown) . 2024 May; 27(5):632-640. PMID: 38771092
Background And Objectives: Endoscopic skull base surgery is a subspecialty field which would benefit significantly from high-fidelity surgical simulators. Giving trainees the opportunity to flatten their learning curve by practicing...
8.
Bouras G, Houtak G, Wick R, Mallawaarachchi V, Roach M, Papudeshi B, et al.
Microb Genom . 2024 May; 10(5). PMID: 38717808
Improvements in the accuracy and availability of long-read sequencing mean that complete bacterial genomes are now routinely reconstructed using hybrid (i.e. short- and long-reads) assembly approaches. Complete genomes allow a...
9.
Yeo K, Connell J, Bouras G, Smith E, Murphy W, Hodge J, et al.
Arch Microbiol . 2024 May; 206(6):248. PMID: 38713383
Describing the microbial community within the tumour has been a key aspect in understanding the pathophysiology of the tumour microenvironment. In head and neck cancer (HNC), most studies on tissue...
10.
Megow A, Bouras G, AlSuliman Y, Cooksley C, Vyskocil E, Murphy W, et al.
Front Surg . 2024 Apr; 11:1338209. PMID: 38638142
Background: Adhesion formation, sinus ostial narrowing, and presence of pathogenic bacteria are associated with poor outcomes following endoscopic sinus surgery (ESS) for chronic rhinosinusitis. Chitogel has been shown to improve...