Robert-Alain Toillon
Overview
Explore the profile of Robert-Alain Toillon including associated specialties, affiliations and a list of published articles.
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Articles
38
Citations
795
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Recent Articles
1.
Pliner L, Laneret N, Roudaut M, Mogrovejo-Valdivia A, Vandenhaute E, Maubon N, et al.
In Vitro Model
. 2025 Jan;
3(4-6):205-218.
PMID: 39872697
Background: Extracellular matrix (ECM) is a three-dimensional (3D) structure found around cells in the tissues of many organisms. It is composed mainly of fibrous proteins, such as collagen and elastin,...
2.
Cicero J, Trouvilliez S, Palma M, Ternier G, Decoster L, Happernegg E, et al.
Exp Hematol Oncol
. 2023 Dec;
12(1):104.
PMID: 38072918
Background: Triple-Negative Breast Cancer is particularly aggressive, and its metastasis to the brain has a significant psychological impact on patients' quality of life, in addition to reducing survival. The development...
3.
Morisse M, Bourhis T, Leveque R, Guilbert M, Cicero J, Palma M, et al.
Front Oncol
. 2023 Aug;
13:661775.
PMID: 37576898
Head and Neck Squamous Cell Carcinoma (HNSCC) remains a cancer with a poor prognosis, with a 5-year survival rate of less than 50%. Although epidermal growth factor receptor (EGFR) is...
4.
Trouvilliez S, Lagadec C, Toillon R
Cancers (Basel)
. 2023 Apr;
15(7).
PMID: 37046604
Larotrectinib and Entrectinib are specific pan-Trk tyrosine kinase inhibitors (TKIs) approved by the Food and Drug Administration (FDA) in 2018 for cancers with an NTRK fusion. Despite initial enthusiasm for...
5.
Denoulet M, Brule M, Anquez F, Vincent A, Schnipper J, Adriaenssens E, et al.
Bioinformatics
. 2023 Jan;
39(1).
PMID: 36629453
Motivation: Nowadays, epigenetic gene regulations are studied in each part of the biology, from embryonic development to diseases such as cancers and neurodegenerative disorders. Currently, to quantify and compare CpG...
6.
Chinigo G, Grolez G, Audero M, Bokhobza A, Bernardini M, Cicero J, et al.
Cancers (Basel)
. 2022 May;
14(9).
PMID: 35565390
Emerging evidence indicates that the TRPM8 channel plays an important role in prostate cancer (PCa) progression, by impairing the motility of these cancer cells. Here, we reveal a novel facet...
7.
Trouvilliez S, Cicero J, Leveque R, Aubert L, Corbet C, Van Outryve A, et al.
J Exp Clin Cancer Res
. 2022 Mar;
41(1):110.
PMID: 35346305
Background: CD44 is a multifunctional membrane glycoprotein. Through its heparan sulfate chain, CD44 presents growth factors to their receptors. We have shown that CD44 and Tropomyosin kinase A (TrkA) form...
8.
Raby L, Volkel P, Hasanpour S, Cicero J, Toillon R, Adriaenssens E, et al.
Cells
. 2021 Nov;
10(11).
PMID: 34831364
Polycomb repressive complex 2 (PRC2) mediates histone H3K27me3 methylation and the stable transcriptional repression of a number of gene expression programs involved in the control of cellular identity during development...
9.
Winter M, Meignan S, Volkel P, Angrand P, Chopin V, Bidan N, et al.
Cells
. 2021 Jul;
10(6).
PMID: 34203746
Tremendous data have been accumulated in the effort to understand chemoresistance of triple negative breast cancer (TNBC). However, modifications in cancer cells surviving combined and sequential treatment still remain poorly...
10.
Dubois C, Kondratska K, Kondratskyi A, Morabito A, Mesilmany L, Farfariello V, et al.
Biochim Biophys Acta Mol Cell Res
. 2021 Apr;
1868(7):119023.
PMID: 33798603
Changes in cytosolic free Ca concentration play a central role in many fundamental cellular processes including muscle contraction, neurotransmission, cell proliferation, differentiation, gene transcription and cell death. Many of these...