Rob J Willems
Overview
Explore the profile of Rob J Willems including associated specialties, affiliations and a list of published articles.
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Articles
12
Citations
456
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0
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Recent Articles
1.
Wagner T, Janice J, Paganelli F, Willems R, Askarian F, Pedersen T, et al.
Int J Microbiol
. 2019 Jan;
2018:1435820.
PMID: 30631364
has undergone a transition to a multidrug-resistant nosocomial pathogen. The population structure of is characterized by a sharp distinction of clades, where the hospital-adapted lineage is primarily responsible for bacteremia....
2.
Lanza V, Baquero F, Luis Martinez J, Ramos-Ruiz R, Gonzalez-Zorn B, Andremont A, et al.
Microbiome
. 2018 Jan;
6(1):11.
PMID: 29335005
Background: Antimicrobial resistance is a major global health challenge. Metagenomics allows analyzing the presence and dynamics of "resistomes" (the ensemble of genes encoding antimicrobial resistance in a given microbiome) in...
3.
Arredondo-Alonso S, Willems R, van Schaik W, Schurch A
Microb Genom
. 2017 Nov;
3(10):e000128.
PMID: 29177087
To benchmark algorithms for automated plasmid sequence reconstruction from short-read sequencing data, we selected 42 publicly available complete bacterial genome sequences spanning 12 genera, containing 148 plasmids. We predicted plasmids...
4.
Freitas A, Tedim A, Francia M, Jensen L, Novais C, Peixe L, et al.
J Antimicrob Chemother
. 2016 Aug;
71(12):3351-3366.
PMID: 27530756
Objectives: Vancomycin-resistant Enterococcus faecium (VREfm) have been increasingly reported since the 1980s. Despite the high number of published studies about VRE epidemiology, the dynamics and evolvability of these microorganisms are...
5.
Tedim A, Ruiz-Garbajosa P, Corander J, Rodriguez C, Canton R, Willems R, et al.
Appl Environ Microbiol
. 2014 Dec;
81(5):1820-31.
PMID: 25548052
The diversity of enterococcal populations from fecal samples from hospitalized (n = 133) and nonhospitalized individuals (n = 173) of different age groups (group I, ages 0 to 19 years;...
6.
de Been M, van Schaik W, Cheng L, Corander J, Willems R
Genome Biol Evol
. 2013 Jul;
5(8):1524-35.
PMID: 23882129
Reasons for the rising clinical impact of the bacterium Enterococcus faecium include the species' rapid acquisition of adaptive genetic elements. Here, we focused on the impact of recombination on the...
7.
Bonten M, Willems R
Ned Tijdschr Geneeskd
. 2012 Sep;
156(38):A5233.
PMID: 22992249
There have recently been 12 outbreaks of infection caused by vancomycin-resistant enterococci (VRE) in Dutch hospitals. Although the first VRE outbreaks were reported almost 12 years ago, such outbreaks remained...
8.
Paganelli F, Willems R, Leavis H
Trends Microbiol
. 2011 Dec;
20(1):40-9.
PMID: 22169461
Enterococcus faecalis and Enterococcus faecium are among the leading causative agents of nosocomial infections and are infamous for their resistance to many antibiotics. They cause difficult-to-treat infections, often originating from...
9.
Laverde Gomez J, Hendrickx A, Willems R, Top J, Sava I, Huebner J, et al.
PLoS One
. 2011 May;
6(4):e16720.
PMID: 21559082
Enterococci are the third leading cause of hospital associated infections and have gained increased importance due to their fast adaptation to the clinical environment by acquisition of antibiotic resistance and...
10.
Leendertse M, Willems R, Giebelen I, Florquin S, van den Pangaart P, Bonten M, et al.
Intensive Care Med
. 2009 Feb;
35(5):924-32.
PMID: 19221713
Purpose: Multiresistant and vancomycin resistant Enterococcus faecium (VRE) can cause serious infections in hospitalized patients with various co-morbid diseases. We investigated the course of VRE peritonitis after cecal ligation and...