Rintaro Okoshi
Overview
Explore the profile of Rintaro Okoshi including associated specialties, affiliations and a list of published articles.
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Articles
12
Citations
264
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Recent Articles
1.
Okoshi R, Shu C, Ihara S, Fukui Y
PLoS One
. 2013 Jan;
8(1):e53298.
PMID: 23308187
Heregulin (HRG) β1 signaling promotes scattering of MCF7 cells by inducing breakdown of adherens and tight junctions. Here, we show that stimulation with HRG-β1 causes the F-actin backbone of junctions...
2.
Okoshi R, Shu C, Ihara S, Fukui Y
PLoS One
. 2012 Jan;
6(12):e29599.
PMID: 22216327
Signal transduction and cell responses after stimulation with heregulin β-1 (HRG) are examined in HCC2998 and MKN45-1 cells, which have been used for a model system to study the formation...
3.
Okoshi R, Kubo N, Nakashima K, Shimozato O, Nakagawara A, Ozaki T
Biochem Biophys Res Commun
. 2011 Feb;
406(1):79-84.
PMID: 21295542
Recently, we have described that CREB (cAMP-responsive element-binding protein) has the ability to transactivate tumor suppressor p53 gene in response to glucose deprivation. In this study, we have found that...
4.
Kubo N, Okoshi R, Nakashima K, Shimozato O, Nakagawara A, Ozaki T
Biochem Biophys Res Commun
. 2010 Nov;
403(3-4):405-11.
PMID: 21093410
It has been shown that MDM2 inhibits the transcriptional and pro-apoptotic activities of p73 but does not promote its proteasomal degradation. In this study, we found that MDM2 indirectly induces...
5.
Bu Y, Suenaga Y, Okoshi R, Sang M, Kubo N, Song F, et al.
Biochem Biophys Res Commun
. 2010 Jun;
397(2):157-62.
PMID: 20529673
NFBD1/MDC1 is a large nuclear protein involved in the early cellular response to DNA damage. Upon DNA damage, NFBD1 has an ability to facilitate the efficient DNA repair. In the...
6.
Yamada C, Ozaki T, Ando K, Suenaga Y, Inoue K, Ito Y, et al.
J Biol Chem
. 2010 Apr;
285(22):16693-703.
PMID: 20353948
Although it has been shown that the gastric tumor suppressor RUNX3 has a growth inhibitory activity, the precise molecular mechanisms behind RUNX3-mediated tumor suppression remained unclear. In this study, we...
7.
Okoshi R, Ando K, Suenaga Y, Sang M, Kubo N, Kizaki H, et al.
Genes Cells
. 2009 Nov;
14(12):1429-40.
PMID: 19930465
Tumor suppressor p53 plays a pivotal role in the regulation of cell fate determination in response to a variety of cellular stress including carbon source depletion. In this study, we...
8.
Ozaki T, Okoshi R, Ono S, Kubo N, Nakagawara A
Biochem Biophys Res Commun
. 2009 Jul;
387(1):143-8.
PMID: 19576172
The expression of tumor suppressor p73 is regulated at mRNA and protein levels. It has been shown that E2F1 acts as a transcriptional activator for p73. In this study, we...
9.
Ozaki T, Okoshi R, Sang M, Kubo N, Nakagawara A
Biochem Biophys Res Commun
. 2009 Jun;
386(1):207-11.
PMID: 19523927
Tumor suppressor p73 plays an important role in the regulation of DNA damage response. E2F-1 acts as a transcriptional regulator for p73. In the present study, we have found that...
10.
Sang M, Ando K, Okoshi R, Koida N, Li Y, Zhu Y, et al.
Genes Cells
. 2009 Jun;
14(7):775-88.
PMID: 19490146
Plk3, one of Polo-like kinase family members, is involved in the regulation of cell cycle progression and DNA damage response. In this study, we found that Plk3 inhibits pro-apoptotic activity...