Richard W Orrell
Overview
Explore the profile of Richard W Orrell including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
62
Citations
5469
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
31.
Mok K, Traynor B, Schymick J, Tienari P, Laaksovirta H, Peuralinna T, et al.
Neurobiol Aging
. 2011 Sep;
33(1):209.e3-8.
PMID: 21925771
We and others have recently reported an association between amyotrophic lateral sclerosis (ALS) and single nucleotide polymorphisms on chromosome 9p21 in several populations. Here we show that the associated haplotype...
32.
Lane R, Roncaroli F, Charles P, McGonagle D, Orrell R
Neuromuscul Disord
. 2011 Aug;
22(2):122-8.
PMID: 21872471
We report two patients with facioscapulohumeral muscular dystrophy (FSHD) presenting with atypical clinical features. Both were found to have antibodies to acetylcholine receptor (AChR-abs) and improved with immunosuppression. AChR-abs have...
33.
Orrell R
Handb Clin Neurol
. 2011 Apr;
101:167-80.
PMID: 21496633
Facioscapulohumeral dystrophy (FSHD) is the third most common muscular dystrophy. It is named for its characteristic involvement of the muscles of the face and upper arm. It is present worldwide,...
34.
Shatunov A, Mok K, Newhouse S, Weale M, Smith B, Vance C, et al.
Lancet Neurol
. 2010 Aug;
9(10):986-94.
PMID: 20801717
Background: Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease of motor neurons that results in progressive weakness and death from respiratory failure, commonly within about 3 years. Previous studies have...
35.
36.
Manjaly Z, Scott K, Abhinav K, Wijesekera L, Ganesalingam J, Goldstein L, et al.
Amyotroph Lateral Scler
. 2010 Mar;
11(5):439-42.
PMID: 20225930
Replicable risk factors for ALS include increasing age, family history and being male. The male: female ratio has been reported as being between 1 and 3. We tested the hypothesis...
37.
Orrell R, Copeland S, Rose M
Cochrane Database Syst Rev
. 2010 Jan;
(1):CD003278.
PMID: 20091543
Background: Winging of the scapula is caused by weakness of the thoracoscapular muscles, which allows the scapula to lift off the chest wall during shoulder movements. In facioscapulohumeral muscular dystrophy...
38.
Orrell R
Br Med Bull
. 2009 Dec;
93:145-59.
PMID: 20015852
Introduction: There is no curative treatment for the common motor neuron diseases, amyotrophic lateral sclerosis (ALS) and spinal muscular atrophy. Nevertheless, there is an increasing volume of published studies. This...
39.
Kearney M, Orrell R, Fahey M, Pandolfo M
Cochrane Database Syst Rev
. 2009 Oct;
(4):CD007791.
PMID: 19821439
Background: Friedreich ataxia is a rare inherited, autosomal recessive, neurological disorder characterised initially by unsteadiness in standing and walking, slowly progressing to wheelchair dependency usually in the late teens or...
40.
Evans R, Harridge S, Velloso C, Yang S, Goldspink G, Orrell R
Amyotroph Lateral Scler
. 2009 Jul;
11(1-2):172-7.
PMID: 19572220
In an animal model of ALS, intramuscular administration of MGF, the IGF-I Ec gene splice variant, improved muscle strength and increased both motor unit and motor neuron survival. Here we...