Richard T Sawyer
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Explore the profile of Richard T Sawyer including associated specialties, affiliations and a list of published articles.
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Articles
16
Citations
289
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Recent Articles
1.
Maier L, Barkes B, Mroz M, Rossman M, Barnard J, Gillespie M, et al.
Respir Med
. 2012 Sep;
106(12):1810-3.
PMID: 22974830
No abstract available.
2.
Condon T, Sawyer R, Fenton M, Riches D
J Leukoc Biol
. 2011 Aug;
90(5):883-95.
PMID: 21807741
This review updates the basic biology of lung DCs and their functions. Lung DCs have taken center stage as cellular therapeutic targets in new vaccine strategies for the treatment of...
3.
Minnicozzi M, Sawyer R, Fenton M
Immunol Rev
. 2011 Jun;
242(1):106-27.
PMID: 21682741
The innate immune system consists of multiple cell types that express germline-encoded pattern recognition receptors that recognize pathogen-associated molecular patterns (PAMPs) or danger-associated molecular patterns (DAMPs). Allergens are frequently found...
4.
Sawyer R, Maier L
Biometals
. 2010 Oct;
24(1):1-17.
PMID: 20981472
During the last decade, there have been concerted efforts to reduce beryllium (Be) exposure in the workplace and thereby reduce potential cases of this occupational lung disorder. Despite these efforts,...
5.
Dobis D, Sawyer R, Gillespie M, Newman L, Maier L, Day B
Am J Respir Cell Mol Biol
. 2009 Nov;
43(4):458-64.
PMID: 19901345
Occupational exposure to beryllium (Be) results in Be sensitization (BeS) that can progress to pulmonary granulomatous inflammation associated with chronic Be disease (CBD). Be-specific lymphocytes are present in the blood...
6.
Plaut M, Sawyer R, Fenton M
J Allergy Clin Immunol
. 2009 Jun;
124(4):671-8.e1.
PMID: 19560803
This article summarizes the proceedings of a 2008 Workshop on Food Allergy Clinical Trials Design co-organized by the National Institute of Allergy and Infectious Diseases and the US Food and...
7.
Dobis D, Sawyer R, Gillespie M, Huang J, Newman L, Maier L, et al.
Am J Respir Crit Care Med
. 2008 Jan;
177(9):1002-11.
PMID: 18218990
Rationale: Occupational exposure to beryllium (Be) can result in chronic granulomatous inflammation characterized by the presence of Be-specific CD4+ T cells. Studies show that oxidative stress plays a role in...
8.
Sato H, Silveira L, Fingerlin T, Dockstader K, Gillespie M, Lagan A, et al.
J Allergy Clin Immunol
. 2007 Jan;
119(3):687-96.
PMID: 17208287
Background: Beryllium stimulates TNF-alpha from chronic beryllium disease (CBD) bronchoalveolar lavage (BAL) cells. Objective: We sought to relate TNF polymorphisms to beryllium-stimulated TNF-alpha production, to the development of CBD, and...
9.
Sawyer R, Fontenot A, Barnes T, Parsons C, Tooker B, Maier L, et al.
Am J Respir Cell Mol Biol
. 2006 Sep;
36(2):191-200.
PMID: 16980557
Beryllium (Be)-antigen presentation to Be-specific CD4(+) T cells from the lungs of patients with chronic beryllium disease (CBD) results in T cell proliferation and TNF-alpha secretion. We tested the hypothesis...
10.
Sawyer R, Abraham J, Daniloff E, Newman L
J Occup Environ Med
. 2005 Dec;
47(12):1218-26.
PMID: 16340702
Objective: We hypothesized that beryllium (Be) might persist in lung granulomas in patients with chronic beryllium disease (CBD). Methods: A total of 33 Be-exposed ceramics workers underwent transbronchial biopsy. They...