Richard T Sawyer
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Explore the profile of Richard T Sawyer including associated specialties, affiliations and a list of published articles.
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Articles
16
Citations
289
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Recent Articles
11.
Sawyer R, Dobis D, Goldstein M, Velsor L, Maier L, Fontenot A, et al.
Free Radic Biol Med
. 2005 Mar;
38(7):928-37.
PMID: 15749389
Beryllium (Be), the etiologic agent of chronic beryllium disease, is a toxic metal that induces apoptosis in human alveolar macrophages. We tested the hypothesis that Be stimulates the formation of...
12.
Sawyer R, Day B, Fadok V, Chiarappa-Zucca M, Maier L, Fontenot A, et al.
Am J Respir Cell Mol Biol
. 2004 Jul;
31(4):470-7.
PMID: 15256386
A beryllium (Be)-ferritin adduct containing 270 pm of Be stimulated proliferation of bronchoalveolar lavage (BAL) lymphocytes from subjects with chronic beryllium disease (CBD) at concentrations 5-6 logs lower than the...
13.
Sawyer R, Parsons C, Fontenot A, Maier L, Gillespie M, Gottschall E, et al.
Am J Respir Cell Mol Biol
. 2004 Feb;
31(1):122-30.
PMID: 14975942
Beryllium (Be) presentation to CD4+ T cells from patients with chronic beryllium disease (CBD) results in T cell activation, and these Be-specific CD4+ T cells undergo clonal proliferation and T-helper...
14.
Influence of MHC class II in susceptibility to beryllium sensitization and chronic beryllium disease
Maier L, McGrath D, Sato H, Lympany P, Welsh K, du Bois R, et al.
J Immunol
. 2003 Dec;
171(12):6910-8.
PMID: 14662898
A glutamic acid at residue 69(Glu(69)) in the HLA-DPB1 gene (Glu(69)) is associated with chronic beryllium disease (CBD) and possibly beryllium sensitization (BeS). This study tested the hypothesis that MHC...
15.
Kittle L, Sawyer R, Fadok V, Maier L, Newman L
Sarcoidosis Vasc Diffuse Lung Dis
. 2002 Jul;
19(2):101-13.
PMID: 12102605
The link between metal-induced apoptosis and granulomatous inflammation in human disease pathogenesis is not established. The presence of TUNEL positive nuclei in chronic beryllium disease (CBD) pulmonary granulomas suggested the...
16.
Sawyer R, Maier L, Kittle L, Newman L
Int Immunopharmacol
. 2002 Jan;
2(2-3):249-61.
PMID: 11811929
Beryllium (Be) is a lightweight and durable metal useful to a variety of manufacturing processes. With the use of Be in industrial settings, a number of health effects were noted...