Richard Roy
Overview
Explore the profile of Richard Roy including associated specialties, affiliations and a list of published articles.
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41
Citations
831
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Recent Articles
1.
Wong C, Jurczak E, Roy R
Cell Rep
. 2024 Oct;
43(10):114851.
PMID: 39392750
During periods of nutrient scarcity, many animals undergo germline quiescence to preserve reproductive capacity, and neurons are often necessary for this adaptation. We show here that starvation causes the release...
2.
Wong C, Kadekar P, Jurczak E, Roy R
PLoS Genet
. 2023 Apr;
19(4):e1010716.
PMID: 37058536
During periods of energetic stress, Caenorhabditis elegans can execute a developmentally quiescent stage called "dauer", during which all germline stem cells undergo a G2 cell cycle arrest. In animals that...
3.
Sun B, Sherrin M, Roy R
Nucleic Acids Res
. 2022 Dec;
51(1):84-98.
PMID: 36504323
During starvation, organisms modify both gene expression and metabolism to adjust to the energy stress. We previously reported that Caenorhabditis elegans lacing AMP-activated protein kinase (AMPK) exhibit transgenerational reproductive defects...
4.
Rashid S, Wong C, Roy R
Dev Biol
. 2021 Feb;
475:265-276.
PMID: 33549550
Developmental plasticity refers the ability of an organism to adapt to various environmental stressors, one of which is nutritional stress. Caenorhabditis elegans require various nutrients to successfully progress through all...
5.
Battaglia A, Kollias P, Dhillon R, Roy R, Tanelli S, Lamer K, et al.
Rev Geophys
. 2020 Jul;
58(3):e2019RG000686.
PMID: 32715303
Spaceborne radars offer a unique three-dimensional view of the atmospheric components of the Earth's hydrological cycle. Existing and planned spaceborne radar missions provide cloud and precipitation information over the oceans...
6.
Wong C, Roy R
Int J Mol Sci
. 2020 Mar;
21(6).
PMID: 32213851
larvae can undergo developmental arrest upon entry into the dauer stage in response to suboptimal growth conditions. Dauer larvae can exit this stage in replete conditions with no reproductive consequence....
7.
Schmeisser S, Li S, Bouchard B, Ruiz M, Des Rosiers C, Roy R
Cell Rep
. 2019 Dec;
29(13):4540-4552.e8.
PMID: 31875559
A growing body of evidence suggests that changes in fat metabolism may have a significant effect on lifespan. Accumulation of lipid deposits in non-adipose tissue appears to be critical for...
8.
Kadekar P, Roy R
PLoS Biol
. 2019 Jun;
17(6):e3000309.
PMID: 31166944
During suboptimal growth conditions, Caenorhabditis elegans larvae undergo a global developmental arrest called "dauer." During this stage, the germline stem cells (GSCs) become quiescent in an AMP-activated Protein Kinase (AMPK)-dependent...
9.
Kadekar P, Chaouni R, Clark E, Kazanets A, Roy R
BMC Genomics
. 2018 Jun;
19(1):462.
PMID: 29907081
Background: Caenorhabditis elegans can endure long periods of environmental stress by altering their development to execute a quiescent state called "dauer". Previous work has implicated LKB1 - the causative gene...
10.
Demoinet E, Roy R
Methods Mol Biol
. 2018 Feb;
1732:565-579.
PMID: 29480500
Environmental variation experienced early in life can result in long-term reproductive consequences. We have recently identified an important role for AMPK in the prevention of transgenerational defects following starvation of...