Richard P Bowater
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Explore the profile of Richard P Bowater including associated specialties, affiliations and a list of published articles.
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34
Citations
587
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Recent Articles
1.
Bowater R, Brazda V
Int J Mol Sci
. 2023 Jan;
24(1).
PMID: 36613851
Interactions between nucleic acids and proteins are some of the most important interactions in biology because they are the cornerstones for fundamental biological processes, such as replication, transcription, and recombination...
2.
Bowater R, Bohalova N, Brazda V
Int J Mol Sci
. 2022 Jun;
23(11).
PMID: 35682854
Cruciforms occur when inverted repeat sequences in double-stranded DNA adopt intra-strand hairpins on opposing strands. Biophysical and molecular studies of these structures confirm their characterization as four-way junctions and have...
3.
Huynh T, Bowater R, Bernuzzi F, Saha S, Wormstone I
Invest Ophthalmol Vis Sci
. 2021 Dec;
62(15):2.
PMID: 34854886
Purpose: Sulforaphane (SFN) is a therapeutic phytochemical agent for many health conditions. SFN-induced cytotoxicity is shown to have promise in preventing posterior capsule opacification (PCO). In the current study, we...
4.
Brazda V, Bohalova N, Bowater R
Gene
. 2021 Nov;
810:146058.
PMID: 34737002
Taking advantage of evolving and improving sequencing methods, human chromosome 8 is now available as a gapless, end-to-end assembly. Thanks to advances in long-read sequencing technologies, its centromere, telomeres, duplicated...
5.
Brazda V, Bartas M, Bowater R
Trends Genet
. 2021 May;
37(8):730-744.
PMID: 33931265
DNA is fundamentally important for all cellular organisms due to its role as a store of hereditary genetic information. The precise and accurate regulation of gene transcription depends primarily on...
6.
Brazda V, Fojta M, Bowater R
Biochem J
. 2020 Jan;
477(2):325-339.
PMID: 31967649
DNA is a fundamentally important molecule for all cellular organisms due to its biological role as the store of hereditary, genetic information. On the one hand, genomic DNA is very...
7.
Helma R, Bazantova P, Petr M, Adamik M, Renciuk D, Tichy V, et al.
Molecules
. 2019 Jun;
24(11).
PMID: 31159174
Expansions of trinucleotide repeats (TNRs) are associated with genetic disorders such as Friedreich's ataxia. The tumor suppressor p53 is a central regulator of cell fate in response to different types...
8.
Liu P, Wang W, Tang J, Bowater R, Bao Y
Food Chem Toxicol
. 2019 Apr;
128:129-136.
PMID: 30940595
Sulforaphane (SFN) has shown anti-cancer effects in cellular and animal studies but its effectiveness has been limited in human studies. Here, the effects of SFN were measured in both human...
9.
Liu P, Wang W, Zhou Z, Smith A, Bowater R, Wormstone I, et al.
Nutrients
. 2018 May;
10(5).
PMID: 29747418
Sulforaphane (SFN) exhibits chemopreventive effects through various mechanisms. However, few studies have focused on the bioactivities of its metabolites. Here, three metabolites derived from SFN were studied, known as sulforaphane...
10.
Liu H, Smith A, Ball S, Bao Y, Bowater R, Wang N, et al.
J Mol Med (Berl)
. 2017 Jan;
95(5):553-564.
PMID: 28083623
Key Message: SFN reduces lens epithelial cell growth, migration, and viability. SFN can promote ER stress and autophagy in lens cells. SFN promotes MAPK signaling, and inhibition of MEK can...