Richard OKennedy
Overview
Explore the profile of Richard OKennedy including associated specialties, affiliations and a list of published articles.
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130
Citations
1834
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Recent Articles
1.
Ma H, Murphy C, Loscher C, OKennedy R
Front Immunol
. 2022 Nov;
13:953726.
PMID: 36341384
Autoantibodies are well known as potentially highly harmful antibodies which attack the host binding to self-antigens, thus causing severe associated diseases and symptoms (e.g. autoimmune diseases). However, detection of autoantibodies...
2.
Cassedy A, OKennedy R
Methods Mol Biol
. 2022 May;
2466:3-22.
PMID: 35585307
Antibodies are an integral part of many biological assays and biotherapeutics. However, the sources from which antibodies are derived frequently contain other contaminants which may interfere with assays or cause...
3.
Regan B, Kinahan D, Daly P, OKennedy R, Collins D
HardwareX
. 2022 May;
11:e00259.
PMID: 35509901
Centrifugal microfluidic devices offer a robust method for low-volume fluid handling by combining low-cost instrumentation with highly integrated automation. Crucial to the efficacy of Lab-on-a-Disc (LoaD) device operation is the...
4.
Cassedy A, Della Bartola M, Parle-McDermott A, Mullins E, OKennedy R
Anal Biochem
. 2021 Dec;
642:114526.
PMID: 34922917
Potato virus Y (PVY) is an abundant and damaging virus which reduces crop yield and marketability. Accurate detection of this economically important virus both in-field and in seed potatoes is...
5.
Ma H, Cassedy A, OFagain C, OKennedy R
J Immunol Methods
. 2021 Nov;
500:113183.
PMID: 34774542
Current diagnosis of acute myocardial infarction involves quantification of circulating cTn levels. This work endeavoured to generate and enhance recombinant antibody fragments targeting various epitopes on the N- and C-terminals...
6.
Rangnoi K, Ruker F, Wozniak-Knopp G, Cvak B, OKennedy R, Yamabhai M
ACS Omega
. 2021 Oct;
6(39):25258-25268.
PMID: 34632185
The application of recombinant antibodies for the analysis of foods and food contaminants is now a major focus, given their capacity to be engineered to tailor their specificity, enhance their...
7.
Regan B, OKennedy R, Collins D
Adv Clin Chem
. 2021 Aug;
104:1-70.
PMID: 34462053
Point-of-care testing (POCT) is a specific format of diagnostic testing that is conducted without accompanying infrastructure or sophisticated instrumentation. Traditionally, such rapid sample-to-answer assays provide inferior analytical performances to their...
8.
Ma H, Cassedy A, OKennedy R
J Immunol Methods
. 2021 Jul;
497:113108.
PMID: 34329690
Cardiovascular disease has remained the world's biggest killer for 30 years. To aid in the diagnosis and prognosis of patients suffering cardiovascular-related disease accurate detection methods are essential. For over...
9.
Ma H, OFagain C, OKennedy R
Biochimie
. 2020 Sep;
177:213-225.
PMID: 32891698
An antibody's stability greatly influences its performance (i.e. its specificity and affinity). Thus, stability is a major issue for researchers and manufacturers, especially with the increasing use of antibodies in...
10.
Spain E, Carrara S, Adamson K, Ma H, OKennedy R, De Cola L, et al.
ACS Omega
. 2019 Aug;
3(12):17116-17124.
PMID: 31458332
An electrochemical biosensor for the detection of cardiac troponin I, cTnI, an important cardiac biomarker, is described. A combination of a novel monoclonal antibody, mAb20B3, and a novel Ir(III)-based metal...