Richard O McCann
Overview
Explore the profile of Richard O McCann including associated specialties, affiliations and a list of published articles.
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Articles
14
Citations
474
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Recent Articles
1.
Zhu H, Zhao J, Zhu B, Collazo J, Gal J, Shi P, et al.
Prostate
. 2011 May;
72(1):72-81.
PMID: 21563192
Background: Proteins on cell surface play important roles during cancer progression and metastasis via their ability to mediate cell-to-cell interactions and navigate the communication between cells and the microenvironment. Methods:...
2.
Wurth M, Schowalter R, Smith E, Moncman C, Dutch R, McCann R
Virology
. 2010 Jun;
404(1):117-26.
PMID: 20537366
Paramyxovirus fusion (F) proteins promote both virus-cell fusion, required for viral entry, and cell-cell fusion, resulting in syncytia formation. We used the F-actin stabilizing drug, jasplakinolide, and the G-actin sequestrant,...
3.
Sakamoto S, McCann R, Dhir R, Kyprianou N
Cancer Res
. 2010 Feb;
70(5):1885-95.
PMID: 20160039
Talin1 is a focal adhesion complex protein that regulates integrin interactions with ECM. This study investigated the significance of talin1 in prostate cancer progression to metastasis in vitro and in...
4.
Smith S, McCann R
Biochemistry
. 2007 Aug;
46(38):10886-98.
PMID: 17722883
Focal adhesion complexes are plasma membrane-associated multicomponent complexes that are essential for integrin-linked signal transduction as well as cell adhesion and cell motility. The cytoskeletal protein Talin1 links integrin adhesion...
5.
Senetar M, Moncman C, McCann R
Cell Motil Cytoskeleton
. 2006 Dec;
64(3):157-73.
PMID: 17183545
The cytoskeletal protein talin serves as an essential link between integrins and the actin cytoskeleton in several similar, but functionally distinct, adhesion complexes, including focal adhesions, costameres, and intercalated disks....
6.
Singiser R, McCann R
BMC Cell Biol
. 2006 Dec;
7:40.
PMID: 17150103
Background: Talins are large, modular cytoskeletal proteins found in animals and amoebozoans such as Dictyostelium discoideum. Since the identification of a second talin gene in vertebrates, it has become increasingly...
7.
Franco S, Senetar M, Simonson W, Huttenlocher A, McCann R
Cell Motil Cytoskeleton
. 2006 Jul;
63(9):563-81.
PMID: 16830345
The cytoskeletal protein Talin1 is a critical link between integrins and the actin cytoskeleton, where it is required for the structural and signaling functions of integrin-containing adhesion complexes. However, the...
8.
Schowalter R, Wurth M, Aguilar H, Lee B, Moncman C, McCann R, et al.
Virology
. 2006 Feb;
350(2):323-34.
PMID: 16500690
The paramyxovirus fusion protein (F) promotes fusion of the viral envelope with the plasma membrane of target cells as well as cell-cell fusion. The plasma membrane is closely associated with...
9.
Poole A, Poore T, Bandhakavi S, McCann R, Hanna D, Glover C
Mol Cell Biochem
. 2005 Dec;
274(1-2):163-70.
PMID: 16342414
The wealth of biochemical, molecular, genetic, genomic, and bioinformatic resources available in S. cerevisiae make it an excellent system to explore the global role of CK2 in a model organism....
10.
Gene duplication and functional divergence during evolution of the cytoskeletal linker protein talin
Senetar M, McCann R
Gene
. 2005 Oct;
362:141-52.
PMID: 16216449
The animal talins are large, modular proteins that link the actin cytoskeleton to the extracellular environment through interactions with beta-integrins and actin. Dictyostelium discoideum has two talins, TalA and TalB,...