Richard M R Coulson
Overview
Explore the profile of Richard M R Coulson including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
16
Citations
2019
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0
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Recent Articles
1.
Lyons P, Peters J, Alberici F, Liley J, Coulson R, Astle W, et al.
Nat Commun
. 2019 Nov;
10(1):5120.
PMID: 31719529
Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare inflammatory disease of unknown cause. 30% of patients have anti-neutrophil cytoplasmic antibodies (ANCA) specific for myeloperoxidase (MPO). Here, we describe a genome-wide...
2.
Monzon-Casanova E, Screen M, Diaz-Munoz M, Coulson R, Bell S, Lamers G, et al.
Nat Immunol
. 2018 Jan;
19(3):267-278.
PMID: 29358707
Antibody affinity maturation occurs in germinal centers (GCs), where B cells cycle between the light zone (LZ) and the dark zone. In the LZ, GC B cells bearing immunoglobulins with...
3.
Ferreira R, Guo H, Coulson R, Smyth D, Pekalski M, Burren O, et al.
Diabetes
. 2014 Feb;
63(7):2538-50.
PMID: 24561305
Diagnosis of the autoimmune disease type 1 diabetes (T1D) is preceded by the appearance of circulating autoantibodies to pancreatic islets. However, almost nothing is known about events leading to this...
4.
Lawler K, Hammond-Kosack K, Brazma A, Coulson R
BMC Syst Biol
. 2013 Jun;
7:52.
PMID: 23805903
Background: Genes for the production of a broad range of fungal secondary metabolites are frequently colinear. The prevalence of such gene clusters was systematically examined across the genome of the...
5.
Field H, Coulson R, Field M
BMC Bioinformatics
. 2013 Apr;
14:141.
PMID: 23621955
Background: Comparative analysis is an essential component to biology. When applied to genomics for example, analysis may require comparisons between the predicted presence and absence of genes in a group...
6.
Pekalski M, Ferreira R, Coulson R, Cutler A, Guo H, Smyth D, et al.
J Immunol
. 2013 Feb;
190(6):2554-66.
PMID: 23418630
As the thymus involutes with age, the maintenance of peripheral naive T cells in humans becomes strongly dependent on peripheral cell division. However, mechanisms that orchestrate homeostatic division remain unclear....
7.
Davison L, Cooper J, Cope N, Wilson N, Smyth D, Howson J, et al.
Hum Mol Genet
. 2011 Oct;
21(2):322-33.
PMID: 21989056
The chromosome 16p13 region has been associated with several autoimmune diseases, including type 1 diabetes (T1D) and multiple sclerosis (MS). CLEC16A has been reported as the most likely candidate gene...
8.
Burren O, Adlem E, Achuthan P, Christensen M, Coulson R, Todd J
Nucleic Acids Res
. 2010 Oct;
39(Database issue):D997-1001.
PMID: 20937630
T1DBase (http://www.t1dbase.org) is web platform, which supports the type 1 diabetes (T1D) community. It integrates genetic, genomic and expression data relevant to T1D research across mouse, rat and human and...
9.
Carlton J, Adams J, Silva J, Bidwell S, Lorenzi H, Caler E, et al.
Nature
. 2008 Oct;
455(7214):757-63.
PMID: 18843361
The human malaria parasite Plasmodium vivax is responsible for 25-40% of the approximately 515 million annual cases of malaria worldwide. Although seldom fatal, the parasite elicits severe and incapacitating clinical...
10.
Coulson R, Touboul N, Ouzounis C
Archaea
. 2007 Mar;
2(2):117-25.
PMID: 17350932
The phylogenetic distribution of the components comprising the transcriptional machinery in the crenarchaeal and euryarchaeal lineages of the Archaea was analyzed in a systematic manner by genome-wide profiling of transcription...